Mesocotical dopamine (DA) inputs to the prefrontal cortex (PFC) play a crtical role in normal
cognitive process and neuropsychiatic pathologies. This DA input regulates aspects of …

Gap junctions are channel-forming structures in contacting plasma membranes that allow
direct metabolic and electrical communication between almost all cell types in the …

Neural-network oscillations at distinct frequencies have been implicated in the encoding,
consolidation and retrieval of information in the hippocampus. Some GABA (γ-aminobutyric …

Persistent symptoms of depression suggest the involvement of stable molecular adaptations
in brain, which may be reflected at the level of chromatin remodeling. We find that chronic …

Physiological rhythmic activity in cortical circuits relies on GABAergic inhibition to balance
excitation and control spike timing. With a focus on recent experimental progress in the …

Behavior-contingent network oscillations bring about transient, functionally coherent
neuronal assemblies in the cerebral cortex, including the hippocampus. Inhibitory input on …

Summry—Gap junctions are widely expressed in the various cell types of the central
nervous system. These specialized membrane intercellular junctions provide the …

We have cloned and functionally characterized a third isoform of a vesicular glutamate
transporter (VGLUT3) expressed on synaptic vesicles that identifies a distinct glutamatergic …

Prefrontal cortical dopamine (DA) modulates pyramidal cell excitability directly and indirectly
by way of its actions on local circuit GABAergic interneurons. DA modulation of interneuronal …

A mixed-signal very large scale integration (VLSI) chip for large scale emulation of spiking
neural networks is presented. The chip contains 2400 silicon neurons with fully …