Cells metabolize nutrients for biosynthetic and bioenergetic needs to fuel growth and
proliferation. The uptake of nutrients from the environment and their intracellular metabolism …

Tumor angiogenesis is necessary for the continued survival and development of tumor cells,
and plays an important role in their growth, invasion, and metastasis. The tumor …

Abstract Phosphoinositide-3 kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
signaling pathway is one of the most important proliferative signaling pathways with critical …

MicroRNAs (miRNAs) have been proven to be involved in cell metastasis and angiogenesis
by interaction with the target mRNAs. Evidence has been confirmed that miR-140-5p is a …

Angiogenesis is essential for tumor growth and metastasis. Understanding the regulation of
tumor angiogenesis has become increasingly important. MicroRNAs (miRNAs) are small …

Background Altered expression levels and structural variations in the vascular endothelial
growth factor (VEGF) have been found to play important roles in cancer development and to …

Abstract Prostate cancer antigen 3 (PCA3) is an overexpressed prostate long non-coding
RNA (lncRNA), transcribed from an intronic region at the long arm of human chromosome …

MicroRNAs (miRNAs, miRs) are small (21–25 nucleotides) endogenous and noncoding
RNAs involved in many cellular processes such as apoptosis, development, proliferation …

One of the hallmarks of cancer is angiogenesis, a series of events leading to the formation of
the abnormal vascular network required for tumor growth, development, progression, and …

Alterations in mTOR signalling molecules, including RICTOR amplification, have been
previously described in many cancers, particularly associated with poor prognosis. In this …