Carbapenem resistance in Acinetobacter baumannii, and their importance in hospital‐acquired infections: a scientific review

M Nguyen, SG Joshi - Journal of applied microbiology, 2021 - academic.oup.com
Carbapenem is an important therapy for serious hospital‐acquired infections and for the
care of patients affected by multidrug‐resistant organisms, specifically Acinetobacter …

β-Lactam potentiators to re-sensitize resistant pathogens: Discovery, development, clinical use and the way forward

L Narendrakumar, M Chakraborty, S Kumari… - Frontiers in …, 2023 - frontiersin.org
β-lactam antibiotics are one of the most widely used and diverse classes of antimicrobial
agents for treating both Gram-negative and Gram-positive bacterial infections. The β-lactam …

Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii

V Tiku, EM Kofoed, D Yan, J Kang, M Xu, M Reichelt… - Scientific reports, 2021 - nature.com
Acinetobacter baumannii is a highly antibiotic resistant Gram-negative bacterium that
causes life-threatening infections in humans with a very high mortality rate. A. baumannii is …

Phenotypic and genotypic characterization of carbapenem-resistant Acinetobacter baumannii isolates from Egypt

A Abouelfetouh, AS Torky, E Aboulmagd - Antimicrobial Resistance & …, 2019 - Springer
Background Antibiotic use is largely under-regulated in Egypt leading to the emergence of
resistant isolates. Carbapenems are last resort agents to treat Acinetobacter baumannii …

High diversity of the emerging pathogen Acinetobacter baumannii and other Acinetobacter spp. in raw manure, biogas plants digestates, and rural and urban …

D Pulami, P Kämpfer, SP Glaeser - Science of The Total Environment, 2023 - Elsevier
Carbapenem-resistant Acinetobacter baumannii causing immense treatment problems in
hospitals. There is still a knowledge gap on the abundance and stability of acquired …

Recent advances in nanoantibiotics against multidrug-resistant bacteria

M Li, Y Liu, Y Gong, X Yan, L Wang, W Zheng… - Nanoscale …, 2023 - pubs.rsc.org
Multidrug-resistant (MDR) bacteria-caused infections have been a major threat to human
health. The abuse of conventional antibiotics accelerates the generation of MDR bacteria …

Cefoperazone/sulbactam: New composites against multiresistant gram negative bacteria?

YH Ku, WL Yu - Infection, Genetics and Evolution, 2021 - Elsevier
Sulbactam, a class A β-lactamase inhibitor, added to cefoperazone either at a fixed 8 mg/L
level of sulbactam or at a level of fixed cefoperazone: sulbactam ratio (2: 1) would constitute …

Carbapenem-resistant Acinetobacter baumannii raises global alarm for new antibiotic regimens

A Thacharodi, A Vithlani, S Hassan, A Alqahtani… - Iscience, 2024 - cell.com
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a top-priority pathogen causing a
nosocomial infection that increases morbidity and mortality. Treatment options for CRAB are …

Novel csuC-DNA nanovaccine based on chitosan candidate vaccine against infection with Acinetobacter baumannii

E Hosseinnezhad-Lazarjani, A Doosti, A Sharifzadeh - Vaccine, 2023 - Elsevier
Background Generating vaccines is a promising and effective method for stopping the
spread of Acinetobacter baumannii (A. baumannii) infections that are becoming more and …

Detection of Antimicrobial Resistance Genes Associated with Carbapenem Resistance from the Whole‐Genome Sequence of Acinetobacter baumannii Isolates from …

M Rao, FA Rashid, S Shukor… - Canadian Journal of …, 2020 - Wiley Online Library
Background. The spread of carbapenem‐resistant A. baumannii (CrAb) is gaining worldwide
attention. The spread of this pathogen is largely due to its ability to acquire various …