Protocols for Plasmodium gametocyte production in vitro: an integrative review and analysis

R Omorou, I Bin Sa'id, M Delves, C Severini… - Parasites & …, 2022 - Springer
Abstract Background The production of Plasmodium gametocytes in vitro is a real challenge.
Many protocols have been described, but few have resulted in the production of viable and …

Reporter parasite lines: valuable tools for the study of Plasmodium biology

Y Miyazaki, S Miyazaki - Trends in Parasitology, 2024 - cell.com
The human malaria parasite Plasmodium falciparum causes the most severe form of malaria
in endemic regions and is transmitted via mosquito bites. To better understand the biology of …

7-N-Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc1 Complex

W Nguyen, MG Dans, I Currie, JK Awalt… - ACS Infectious …, 2023 - ACS Publications
The development of new antimalarials is required because of the threat of resistance to
current antimalarial therapies. To discover new antimalarial chemotypes, we screened the …

Analysis of sex-specific lipid metabolism of Plasmodium falciparum points to the importance of sphingomyelin for gametocytogenesis

MC Ridgway, D Cihalova, SHJ Brown… - Journal of cell …, 2022 - journals.biologists.com
Male and female Plasmodium falciparum gametocytes are the parasite lifecycle stage
responsible for transmission of malaria from the human host to the mosquito vector. Not only …

[HTML][HTML] Analysis of Plasmodium falciparum Mitochondrial Electron Transport Chain Activity Using Seahorse XFe96 Extracellular Flux Assays

SS Ramesh, D Cihalova, E Rajendran… - Bio …, 2023 - ncbi.nlm.nih.gov
The mitochondrial electron transport chain (ETC) is a multi-component pathway that
mediates the transfer of electrons from metabolic reactions that occur in the mitochondrion to …

Analysis of sex-specific lipid metabolism in P. falciparum gametocytes points to importance of sphingomyelin for gametocytogenesis

MC Ridgway, D Cihalova, SHJ Brown, P Tran… - bioRxiv, 2021 - biorxiv.org
Male and female Plasmodium falciparum gametocytes are the parasite lifecycle stage
responsible for transmission of malaria from the human host to mosquito vector. Not only are …