A dynamic subpopulation of CRISPR–Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage
MJ Stoltzfus, RE Workman, NC Keith, JW Modell - Nature microbiology, 2024 - nature.com
Many CRISPR–Cas (clustered regularly interspaced short palindromic repeats and CRISPR-
associated protein) systems, which provide bacteria with adaptive immunity against phages …
associated protein) systems, which provide bacteria with adaptive immunity against phages …
Isoform-specific RNA structure determination using Nano-DMS-MaP
RNA structure determination is essential to understand how RNA carries out its diverse
biological functions. In cells, RNA isoforms are readily expressed with partial variations …
biological functions. In cells, RNA isoforms are readily expressed with partial variations …
Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays
A Santiago-Frangos, WS Henriques… - Nature Structural & …, 2023 - nature.com
Bacteria and archaea acquire resistance to viruses and plasmids by integrating fragments of
foreign DNA into the first repeat of a CRISPR array. However, the mechanism of site-specific …
foreign DNA into the first repeat of a CRISPR array. However, the mechanism of site-specific …
Standardized Iterative Genome Editing Method for Escherichia coli Based on CRISPR-Cas9
H Fang, J Zhao, X Zhao, N Dong, Y Zhao… - ACS Synthetic …, 2024 - ACS Publications
The introduction of complex biosynthetic pathways into the hosts' chromosomes is gaining
attention with the development of synthetic biology. While CRISPR-Cas9 has been widely …
attention with the development of synthetic biology. While CRISPR-Cas9 has been widely …
The intricate pathogenicity of Group A Streptococcus: A comprehensive update
H Bergsten, V Nizet - Virulence, 2024 - Taylor & Francis
ABSTRACT Group A Streptococcus (GAS) is a versatile pathogen that targets human
lymphoid, decidual, skin, and soft tissues. Recent advancements have shed light on its …
lymphoid, decidual, skin, and soft tissues. Recent advancements have shed light on its …
Protein-mediated genome folding allosterically enhances site-specific integration of foreign DNA into CRISPRs
Bacteria and archaea acquire resistance to viruses and plasmids by integrating fragments of
foreign DNA into the first repeat of a CRISPR array. However, the mechanism of site-specific …
foreign DNA into the first repeat of a CRISPR array. However, the mechanism of site-specific …
Crispri-mediated gene silencing in biofilm cycle and quorum sensing
A Arora - Gene Editing in Plants: Crispr-Cas and Its Applications, 2024 - Springer
Biofilm is an assembly of architecturally, bacterial mono-species with different functional
attributes but with similar genetical makeup. It is generally formed when multicellularity is …
attributes but with similar genetical makeup. It is generally formed when multicellularity is …
[HTML][HTML] Application and progress of CRISPR/Cas9 gene editing in B-cell lymphoma: a narrative review
Y Jin, H Wu, J Liu, WC Cho, G Song - Translational Cancer …, 2024 - ncbi.nlm.nih.gov
Application and progress of CRISPR/Cas9 gene editing in B-cell lymphoma: a narrative review
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …
Virulence regulates and boosts CRISPR-Cas9 immunity in Group B Streptococcus
CRISPR-Cas9 immune systems protect bacteria from foreign DNA. However, immune
efficiency is constrained by Cas9 off-target cleavages and toxicity. How bacteria regulate …
efficiency is constrained by Cas9 off-target cleavages and toxicity. How bacteria regulate …
RNA therapeutics for the treatment of blood disorders.
AD Ngo, HL Nguyen, S Caglayan… - Progress in Molecular …, 2024 - europepmc.org
Blood disorders are defined as diseases related to the structure, function, and formation of
blood cells. These diseases lead to increased years of life loss, reduced quality of life, and …
blood cells. These diseases lead to increased years of life loss, reduced quality of life, and …