Wnt/β-catenin signaling is implicated in many physiological processes, including
development, tissue homeostasis, and tissue regeneration. In human cancers, Wnt/β-catenin …

Phenotypic and functional heterogeneity is one of the hallmarks of human cancers. Tumor
genotype variations among tumors within different patients are known as interpatient …

Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

Colorectal cancer (CRC) is the fourth leading cause of cancer death worldwide, and
constitutive activation of the Wnt signaling pathway is universal in most CRC cases. Wnt …

Abstract Background/Aim Probiotics have been suggested as prophylactic measure in colon
carcinogenesis. This study aimed at determining the potential prophylactic activity of …

The Wnt/β-catenin signaling pathway is a growth control pathway involved in various
biological processes as well as the development and progression of cancer. Colorectal …

Studies over the past four decades have elucidated the role of Wnt/β-catenin mediated
regulation in cell proliferation, differentiation and migration. These processes are …

The prognosis after curative resection of gastric cancer (GC) remains unsatisfactory, and
thus, the development of treatments involving alternative molecular and genetic targets is …

Vesicular acidification and trafficking are associated with various cellular processes.
However, their pathologic relevance to cancer remains elusive. We identified …

Despite the implication of Wnt signalling in radioresistance, the underlying mechanisms are
unknown. Here we find that high Wnt signalling is associated with radioresistance in …