Free radical properties, source and targets, antioxidant consumption and health

G Martemucci, C Costagliola, M Mariano, L D'andrea… - Oxygen, 2022 - mdpi.com
Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

Oxidative stress, inflammation and colorectal cancer: an overview

A Bardelčíková, J Šoltys, J Mojžiš - Antioxidants, 2023 - mdpi.com
Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …

The impact of oxidative stress in human pathology: Focus on gastrointestinal disorders

R Vona, L Pallotta, M Cappelletti, C Severi… - Antioxidants, 2021 - mdpi.com
Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …

Oxidative stress and redox-modulating therapeutics in inflammatory bowel disease

AR Bourgonje, M Feelisch, KN Faber, A Pasch… - Trends in molecular …, 2020 - cell.com
Inflammatory bowel disease (IBD) is associated with the production of reactive species that
target cysteine redox switches in proteins, thereby affecting gene regulation, DNA damage …

[HTML][HTML] Role of ROS and nutritional antioxidants in human diseases

Z Liu, Z Ren, J Zhang, CC Chuang… - Frontiers in …, 2018 - frontiersin.org
The overproduction of reactive oxygen species (ROS) has been implicated in the
development of various chronic and degenerative diseases such as cancer, respiratory …

Pathomechanisms of oxidative stress in inflammatory bowel disease and potential antioxidant therapies

T Tian, Z Wang, J Zhang - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease whose incidence has
risen worldwide in recent years. Accumulating evidence shows that oxidative stress plays an …

Ginseng root extract attenuates inflammation by inhibiting the MAPK/NF-κB signaling pathway and activating autophagy and p62-Nrf2-Keap1 signaling in vitro and in …

S Yang, F Li, S Lu, L Ren, S Bian, M Liu, D Zhao… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Panax ginseng CA Meyer is a type of herbal plant that has
frequently been used in many Asian countries to treat a variety of diseases. Ginseng is …

[HTML][HTML] Personalized redox medicine in inflammatory bowel diseases: an emerging role for HIF-1α and NRF2 as therapeutic targets

AR Bourgonje, D Kloska, A Grochot-Przęczek… - Redox Biology, 2023 - Elsevier
Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative
colitis (UC), are intimately associated with inflammation and overproduction of reactive …

[HTML][HTML] Gold nanoparticles-embedded ceria with enhanced antioxidant activities for treating inflammatory bowel disease

M Li, J Liu, L Shi, C Zhou, M Zou, D Fu, Y Yuan, C Yao… - Bioactive Materials, 2023 - Elsevier
The excessive reactive oxygen species (ROS) is a hallmark associated with the initiation
and progression of inflammatory bowel disease (IBD), which execrably form a vicious cycle …

Catechins and their therapeutic benefits to inflammatory bowel disease

FY Fan, LX Sang, M Jiang - Molecules, 2017 - mdpi.com
Catechins are natural polyphenolic phytochemicals that exist in food and medicinal plants,
such as tea, legume and rubiaceae. An increasing number of studies have associated the …