There are various types of receptors in the central nervous system (CNS). G protein-coupled
receptors (GPCRs) have the highest expression with a wide range of physiological …

Context The incidence of anxiety, which stems from both intrinsic and extrinsic factors, has
been increasing worldwide. Various methods by which it can be treated or prevented have …

The assumption that the transmission of social behaviors and political preferences is purely
cultural has been challenged repeatedly over the last 40 years by the combined evidence of …

Heterozygous HNF1A gene mutations can cause maturity onset diabetes of the young 3
(MODY3), characterized by insulin secretion defects. However, specific mechanisms of …

Background Hypoxic–ischemic encephalopathy (HIE) is a severe anoxic brain injury that
leads to premature mortality or long-term disabilities in infants. Neuroinflammation is a vital …

Arachidonic acid metabolites epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates
(HETEs) are important regulators of myocardial blood flow and coronary vascular resistance …

The metabolic actions of the ghrelin gene‐derived peptide obestatin are still unclear. We
investigated obestatin effects in vitro, on adipocyte function, and in vivo, on insulin …

GPR39 is a vertebrate G protein-coupled receptor related to the ghrelin/neurotensin receptor
subfamily. The receptor is expressed in a range of tissues including the pancreas …

Background: Zinc may act as a neurotransmitter in the central nervous system by activation
of the GPR39 metabotropic receptors. Methods: In the present study, we investigated …

The receptor for the orexigenic peptide, ghrelin, is one of the most constitutively active 7TM
receptors known, as demonstrated under in vitro conditions. Change in expression of a …