Internal friction, which reflects the “roughness” of the energy landscape, plays an important
role for proteins by modulating the dynamics of their folding and other conformational …

Frictional effects due to the chain itself, rather than the solvent, may have a significant effect
on protein dynamics. Experimentally, such “internal friction” has been investigated by …

We hypothesize that the first step of aggregation of disordered proteins, such as α-synuclein,
is controlled by the rate of backbone reconfiguration. When reconfiguration is fast …

The kinetics of loop formation, ie, the occurrence of contact between two atoms of a
polypeptide, remains the focus of continuing interest. One of the reasons is that contact …

In live tissue, alterations in metabolism induce changes in the fluorescence decay of the
biological coenzyme NAD (P) H, the mechanism of which is not well understood. In this …

Significant effect of coupling between the electron donor and acceptor groups in
intramolecular charge transfer (ICT) dynamics has been demonstrated by comparing the …

Recent experiments showed that the reconfiguration dynamics of unfolded proteins are often
adequately described by simple polymer models. In particular, the Rouse model with …

Whether single-molecule trajectories, observed experimentally or in molecular simulations,
can be described using simple models such as biased diffusion is a subject of considerable …

Diffusional dynamics of the donor–acceptor distance are responsible for the appearance of
a new time scale of diffusion over the distance of electronic tunneling in electron-transfer …

Understanding the excited‐state properties of thioflavin‐T (ThT) has been of immense
importance, because of its efficient amyloid‐sensing ability related to neurodegenerative …