Ethnobotany and the role of plant natural products in antibiotic drug discovery
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
Synthetic biology strategies for microbial biosynthesis of plant natural products
Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …
Biosynthesis of medicinal tropane alkaloids in yeast
P Srinivasan, CD Smolke - Nature, 2020 - nature.com
Tropane alkaloids from nightshade plants are neurotransmitter inhibitors that are used for
treating neuromuscular disorders and are classified as essential medicines by the World …
treating neuromuscular disorders and are classified as essential medicines by the World …
OrthoFinder: phylogenetic orthology inference for comparative genomics
Here, we present a major advance of the OrthoFinder method. This extends OrthoFinder's
high accuracy orthogroup inference to provide phylogenetic inference of orthologs, rooted …
high accuracy orthogroup inference to provide phylogenetic inference of orthologs, rooted …
Fern genomes elucidate land plant evolution and cyanobacterial symbioses
Ferns are the closest sister group to all seed plants, yet little is known about their genomes
other than that they are generally colossal. Here, we report on the genomes of Azolla …
other than that they are generally colossal. Here, we report on the genomes of Azolla …
A universal probe set for targeted sequencing of 353 nuclear genes from any flowering plant designed using k-medoids clustering
MG Johnson, L Pokorny, S Dodsworth… - Systematic …, 2019 - academic.oup.com
Sequencing of target-enriched libraries is an efficient and cost-effective method for obtaining
DNA sequence data from hundreds of nuclear loci for phylogeny reconstruction. Much of the …
DNA sequence data from hundreds of nuclear loci for phylogeny reconstruction. Much of the …
The hornwort genome and early land plant evolution
J Zhang, XX Fu, RQ Li, X Zhao, Y Liu, MH Li… - Nature plants, 2020 - nature.com
Hornworts, liverworts and mosses are three early diverging clades of land plants, and
together comprise the bryophytes. Here, we report the draft genome sequence of the …
together comprise the bryophytes. Here, we report the draft genome sequence of the …
Divergent evolutionary trajectories of bryophytes and tracheophytes from a complex common ancestor of land plants
The origin of plants and their colonization of land fundamentally transformed the terrestrial
environment. Here we elucidate the basis of this formative episode in Earth history through …
environment. Here we elucidate the basis of this formative episode in Earth history through …
Evolution of plant hormone response pathways
MA Blázquez, DC Nelson… - Annual Review of Plant …, 2020 - annualreviews.org
This review focuses on the evolution of plant hormone signaling pathways. Like the
chemical nature of the hormones themselves, the signaling pathways are diverse. Therefore …
chemical nature of the hormones themselves, the signaling pathways are diverse. Therefore …
Phylotranscriptomic analysis of the origin and early diversification of land plants
Reconstructing the origin and evolution of land plants and their algal relatives is a
fundamental problem in plant phylogenetics, and is essential for understanding how critical …
fundamental problem in plant phylogenetics, and is essential for understanding how critical …