Natural and synthetic bioinks for 3D bioprinting

R Khoeini, H Nosrati, A Akbarzadeh… - Advanced …, 2021 - Wiley Online Library
Bioprinting offers tremendous potential in the fabrication of functional tissue constructs for
replacement of damaged or diseased tissues. Among other fabrication methods used in …

[HTML][HTML] The extracellular matrix of hematopoietic stem cell niches

C Lee-Thedieck, P Schertl, G Klein - Advanced Drug Delivery Reviews, 2022 - Elsevier
Hematopoietic stem cells (HSCs) are the life-long source of all types of blood cells. Their
function is controlled by their direct microenvironment, the HSC niche in the bone marrow …

Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation

J Swift, IL Ivanovska, A Buxboim, T Harada… - Science, 2013 - science.org
Introduction Tissues can be soft like brain, bone marrow, and fat, which bear little
mechanical stress, or stiff like muscle, cartilage, and bone, which sustain high levels of …

Mechanical memory and dosing influence stem cell fate

C Yang, MW Tibbitt, L Basta, KS Anseth - Nature materials, 2014 - nature.com
We investigated whether stem cells remember past physical signals and whether these can
be exploited to dose cells mechanically. We found that the activation of the Yes-associated …

Morphological features of IFN-γ–stimulated mesenchymal stromal cells predict overall immunosuppressive capacity

MW Klinker, RA Marklein, JL Lo Surdo… - Proceedings of the …, 2017 - National Acad Sciences
Human mesenchymal stromal cell (MSC) lines can vary significantly in their functional
characteristics, and the effectiveness of MSC-based therapeutics may be realized by finding …

Physical, Spatial, and Molecular Aspects of Extracellular Matrix of In Vivo Niches and Artificial Scaffolds Relevant to Stem Cells Research

M Akhmanova, E Osidak, S Domogatsky… - Stem cells …, 2015 - Wiley Online Library
Extracellular matrix can influence stem cell choices, such as self‐renewal, quiescence,
migration, proliferation, phenotype maintenance, differentiation, or apoptosis. Three aspects …

Marrow-inspired matrix cues rapidly affect early fate decisions of hematopoietic stem and progenitor cells

JS Choi, BAC Harley - Science advances, 2017 - science.org
Hematopoiesis is the physiological process where hematopoietic stem cells (HSCs)
continuously generate the body's complement of blood and immune cells within unique …

Microtubules control nuclear shape and gene expression during early stages of hematopoietic differentiation

S Biedzinski, G Agsu, B Vianay, M Delord… - The EMBO …, 2020 - embopress.org
Hematopoietic stem and progenitor cells (HSPC) can differentiate into all hematopoietic
lineages to support hematopoiesis. Cells from the myeloid and lymphoid lineages fulfill …

The use of covalently immobilized stem cell factor to selectively affect hematopoietic stem cell activity within a gelatin hydrogel

BP Mahadik, SP Haba, LJ Skertich, BAC Harley - Biomaterials, 2015 - Elsevier
Hematopoietic stem cells (HSCs) are a rare stem cell population found primarily in the bone
marrow and responsible for the production of the body's full complement of blood and …

The effects of locomotion on bone marrow mesenchymal stem cell fate: insight into mechanical regulation and bone formation

Y Sun, Y Yuan, W Wu, L Lei, L Zhang - Cell & bioscience, 2021 - Springer
Bone marrow mesenchymal stem cells (BMSCs) refer to a heterogeneous population of cells
with the capacity for self-renewal. BMSCs have multi-directional differentiation potential and …