Hematopoietic stem cells (HSCs) are the life-long source of all types of blood cells. Their function is controlled by their direct microenvironment, the HSC niche in the bone marrow …
J Swift, IL Ivanovska, A Buxboim, T Harada… - Science, 2013 - science.org
Introduction Tissues can be soft like brain, bone marrow, and fat, which bear little mechanical stress, or stiff like muscle, cartilage, and bone, which sustain high levels of …
We investigated whether stem cells remember past physical signals and whether these can be exploited to dose cells mechanically. We found that the activation of the Yes-associated …
MW Klinker, RA Marklein, JL Lo Surdo… - Proceedings of the …, 2017 - National Acad Sciences
Human mesenchymal stromal cell (MSC) lines can vary significantly in their functional characteristics, and the effectiveness of MSC-based therapeutics may be realized by finding …
M Akhmanova, E Osidak, S Domogatsky… - Stem cells …, 2015 - Wiley Online Library
Extracellular matrix can influence stem cell choices, such as self‐renewal, quiescence, migration, proliferation, phenotype maintenance, differentiation, or apoptosis. Three aspects …
Hematopoiesis is the physiological process where hematopoietic stem cells (HSCs) continuously generate the body's complement of blood and immune cells within unique …
S Biedzinski, G Agsu, B Vianay, M Delord… - The EMBO …, 2020 - embopress.org
Hematopoietic stem and progenitor cells (HSPC) can differentiate into all hematopoietic lineages to support hematopoiesis. Cells from the myeloid and lymphoid lineages fulfill …
Hematopoietic stem cells (HSCs) are a rare stem cell population found primarily in the bone marrow and responsible for the production of the body's full complement of blood and …
Y Sun, Y Yuan, W Wu, L Lei, L Zhang - Cell & bioscience, 2021 - Springer
Bone marrow mesenchymal stem cells (BMSCs) refer to a heterogeneous population of cells with the capacity for self-renewal. BMSCs have multi-directional differentiation potential and …