The search for ideal brucellosis vaccines remains active today. Currently, no licensed
human or canine anti-brucellosis vaccines are available. In bovines, the most successful …

Modern adjuvants should induce strong and balanced immune responses, and it is often
desirable to induce specific types of immunity. As an example, efficient Th1-immunity …

Brucella spp. are Gram-negative, facultative intracellular bacteria that cause brucellosis in
humans and various animals. The threat of brucellosis has increased, yet currently available …

The success of subunit vaccines has been hampered by the problems of weak or short-term
immunity and the lack of availability of nontoxic, potent adjuvants. It would be desirable to …

Knowing the inherent stimulatory properties of the lipid moiety of bacterial lipoproteins, we
first hypothesized that Brucella abortus outer membrane protein (Omp) 16 lipoprotein would …

Pseudomonas aeruginosa (PA) is a Gram-negative pathogen that the World Health
Organization has ranked as a priority 1 (critical) threat. One potential prophylactic approach …

Brucella abortus is a Gram-negative facultative and intracellular bacteria, it causes bovine
brucellosis, a zoonotic disease that is responsible for considerable economic loss to owners …

Background Surface proteins are a key to a deeper understanding of the behaviour of Gram-
positive bacteria interacting with the human gastro-intestinal tract. Such proteins contribute …

Vaccination is the most important approach to counteract infectious diseases. Thus, the
development of new and improved vaccines for existing, emerging, and re-emerging …

Generation of a CD8+ response to extracellular antigen requires processing of the antigen
by antigen presenting cells (APC) and cross-presentation to CD8+ T cell receptors via MHC …