The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome

NP Daskalakis, RC Bagot, KJ Parker… - …, 2013 - Elsevier
Stressful experiences during early-life can modulate the genetic programming of specific
brain circuits underlying emotional and cognitive aspects of behavioral adaptation to …

The impact of environmental and social factors on learning abilities: a meta‐analysis

CT Lambert, LM Guillette - Biological Reviews, 2021 - Wiley Online Library
Since the 1950s, researchers have examined how differences in the social and asocial
environment affect learning in rats, mice, and, more recently, a variety of other species …

Early social enrichment rescues adult behavioral and brain abnormalities in a mouse model of fragile X syndrome

D Oddi, E Subashi, S Middei, L Bellocchio… - …, 2015 - nature.com
Converging lines of evidence support the use of environmental stimulation to ameliorate the
symptoms of a variety of neurodevelopmental disorders. Applying these interventions at very …

Long-term behavioral effects of prenatal stress in the Fmr1-knock-out mouse model for fragile X syndrome

V Petroni, E Subashi, M Premoli, M Memo… - Frontiers in Cellular …, 2022 - frontiersin.org
Fragile X syndrome (FXS) is a major neurodevelopmental disorder and the most common
monogenic cause of autism spectrum disorder (ASD). FXS is caused by a mutation in the X …

Mother–young bonding: Neurobiological aspects and maternal biochemical signaling in altricial domesticated mammals

C Bienboire-Frosini, M Marcet-Rius, A Orihuela… - Animals, 2023 - mdpi.com
Simple Summary Mother–young bonding is an essential process that increases newborn
survival through selective maternal care. In this mechanism, olfactory, visual, auditory, and …

Specific profile of ultrasonic communication in a mouse model of neurodevelopmental disorders

M Premoli, SA Bonini, A Mastinu, G Maccarinelli… - Scientific Reports, 2019 - nature.com
Mice emit ultrasonic vocalizations (USVs) in different social conditions: pups maternal
separation, juveniles play, adults mating and social investigation. The USVs measurement …

MSK1 regulates homeostatic and experience-dependent synaptic plasticity

SAL Corrêa, CJ Hunter, O Palygin… - Journal of …, 2012 - Soc Neuroscience
The ability of neurons to modulate synaptic strength underpins synaptic plasticity, learning
and memory, and adaptation to sensory experience. Despite the importance of synaptic …

Early-life risk factors for panic and separation anxiety disorder: insights and outstanding questions arising from human and animal studies of CO2 sensitivity

M Battaglia, A Ogliari, F D'Amato, R Kinkead - … & Biobehavioral Reviews, 2014 - Elsevier
Genetically informative studies showed that genetic and environmental risk factors act and
interact to influence liability to (a) panic disorder,(b) its childhood precursor separation …

Long term effects of early life stress on HPA circuit in rodent models

L Babicola, R Ventura, SL D'Addario, D Ielpo… - Molecular and Cellular …, 2021 - Elsevier
Adaptation to environmental challenges represents a critical process for survival, requiring
the complex integration of information derived from both external cues and internal signals …

Implications of temporal variation in maternal care for the prediction of neurobiological and behavioral outcomes in offspring.

C Jensen Peña, FA Champagne - Behavioral neuroscience, 2013 - psycnet.apa.org
Abstract Previous studies in Long-Evans rats demonstrated a significant relationship
between variation in pup licking/grooming and arched-back nursing (LG-ABN) and offspring …