Immunogenic cell stress and death
Dying mammalian cells emit numerous signals that interact with the host to dictate the
immunological correlates of cellular stress and death. In the absence of reactive antigenic …
immunological correlates of cellular stress and death. In the absence of reactive antigenic …
Endoplasmic reticulum stress signals in the tumour and its microenvironment
X Chen, JR Cubillos-Ruiz - Nature Reviews Cancer, 2021 - nature.com
Protein handling, modification and folding in the endoplasmic reticulum (ER) are tightly
regulated processes that determine cell function, fate and survival. In several tumour types …
regulated processes that determine cell function, fate and survival. In several tumour types …
Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors
Conventional chemotherapeutics have been developed into clinically useful agents based
on their ability to preferentially kill malignant cells, generally owing to their elevated …
on their ability to preferentially kill malignant cells, generally owing to their elevated …
Immunosurveillance in clinical cancer management
The progression of cancer involves a critical step in which malignant cells escape from
control by the immune system. Antineoplastic agents are particularly efficient when they …
control by the immune system. Antineoplastic agents are particularly efficient when they …
[HTML][HTML] Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
L Galluzzi, I Vitale, S Warren, S Adjemian… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …
response associated with immunological memory, provided they display sufficient …
Detection of immunogenic cell death and its relevance for cancer therapy
Chemotherapy, radiation therapy, as well as targeted anticancer agents can induce clinically
relevant tumor-targeting immune responses, which critically rely on the antigenicity of …
relevant tumor-targeting immune responses, which critically rely on the antigenicity of …
Massively evoking immunogenic cell death by focused mitochondrial oxidative stress using an AIE luminogen with a twisted molecular structure
Immunogenic cell death (ICD) provides momentous theoretical principle for modern cancer
immunotherapy. However, the currently available ICD inducers are still very limited and …
immunotherapy. However, the currently available ICD inducers are still very limited and …
Cell death, therapeutics, and the immune response in cancer
Induction of cell death is inexorably linked with cancer therapy, but this can also initiate
wound-healing processes that have been linked to cancer progression and therapeutic …
wound-healing processes that have been linked to cancer progression and therapeutic …
Nitric oxide induces immunogenic cell death and potentiates cancer immunotherapy
Tumor cells undergoing immunogenic cell death (ICD) release immunogenic damage-
associated molecular patterns (DAMPs) to trigger a long-term protective antitumor response …
associated molecular patterns (DAMPs) to trigger a long-term protective antitumor response …
Immunogenic cell death induction by ionizing radiation
M Zhu, M Yang, J Zhang, Y Yin, X Fan… - Frontiers in …, 2021 - frontiersin.org
Immunogenic cell death (ICD) is a form of regulated cell death (RCD) induced by various
stresses and produces antitumor immunity via damage-associated molecular patterns …
stresses and produces antitumor immunity via damage-associated molecular patterns …