A review on the development of bacterial multi-epitope recombinant protein vaccines via reverse vaccinology

Y Li, MHR Farhan, X Yang, Y Guo, Y Sui, J Chu… - International Journal of …, 2024 - Elsevier
Bacterial vaccines play a crucial role in combating bacterial infectious diseases. Apart from
the prevention of disease, bacterial vaccines also help to reduce the mortality rates in …

Vaccine development for bacterial pathogens: Advances, challenges and prospects

IE Mba, HC Sharndama… - Tropical Medicine & …, 2023 - Wiley Online Library
The advent and use of antimicrobials have played a key role in treating potentially life‐
threatening infectious diseases, improving health, and saving the lives of millions of people …

[HTML][HTML] Comparison of antibacterial activity and cytotoxicity of silver nanoparticles and silver-loaded montmorillonite and saponite

A Gil-Korilis, M Cojocaru, M Berzosa, C Gamazo… - Applied Clay …, 2023 - Elsevier
Although silver nanoparticles are known for their antibacterial activity, little research has
been carried out on what synthesis method provides the most effective particles. In this …

Recent advances in enterotoxin vaccine adjuvants

JW Crothers, EB Norton - Current Opinion in Immunology, 2023 - Elsevier
Enterotoxin adjuvants have been researched for their ability to promote immunity to co-
delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be …

A Polyvalent Adhesin–Toxoid Multiepitope-Fusion-Antigen-Induced Functional Antibodies against Five Enterotoxigenic Escherichia coli Adhesins (CS7, CS12, CS14 …

S Li, H Seo, I Upadhyay, W Zhang - Microorganisms, 2023 - mdpi.com
The increasing prevalence and association with moderate-to-severe diarrhea make
enterotoxigenic Escherichia coli (ETEC) adhesins CS7, CS12, CS14, CS17, and CS21 …

Intramuscularly Administered Enterotoxigenic Escherichia coli (ETEC) Vaccine Candidate MecVax Prevented H10407 Intestinal Colonization in an Adult Rabbit …

I Upadhyay, KL Lauder, S Li, G Ptacek… - Microbiology …, 2022 - Am Soc Microbiol
Currently, there are no vaccines licensed for enterotoxigenic Escherichia coli (ETEC), a
leading cause of children's diarrhea in developing countries and the most common cause of …

Protein-based vaccine candidate MecVax broadly protects against enterotoxigenic Escherichia coli intestinal colonization in a rabbit model

I Upadhyay, SMD Parvej, Y Shen, S Li… - Infection and …, 2023 - Am Soc Microbiol
There are no vaccines licensed against enterotoxigenic Escherichia coli (ETEC), a leading
cause of children's diarrhea and the most common cause of travelers' diarrhea. Multivalent …

Evaluation of Multivalent Enterotoxigenic Escherichia coli Vaccine Candidate MecVax Antigen Dose-Dependent Effect in a Murine Model

H Seo, Q Duan, I Upadhyay… - Applied and environmental …, 2022 - Am Soc Microbiol
There are no licensed vaccines against enterotoxigenic Escherichia coli (ETEC), a leading
cause of children's diarrhea and travelers' diarrhea. Recently, protein-based vaccine …

Special Issue on Enterotoxigenic Escherichia coli (ETEC) Vaccines: ETEC Infection and Vaccine-Mediated Immunity

FJ Cassels, I Khalil, AL Bourgeois, RI Walker - Microorganisms, 2024 - mdpi.com
Enterotoxigenic Escherichia coli (ETEC) is the most prevalent bacterial pathogen causing
young children to suffer acute watery diarrhea in Low-and Middle-Income Countries …

Unleashing the Immune Arsenal: Development of Broad-spectrum Multiepitope Bluetongue Vaccine Targeting Conserved T Cell Epitopes of Structural Proteins

HB Kolla, A Kumar, M Dutt, RH Nanjunadappa… - bioRxiv, 2024 - biorxiv.org
Bluetongue (BT) is a severe arboviral disease affecting sheep, cows, and other wild
ruminants, caused by the Bluetongue virus (BTV). The virus has evolved into over 32 …