The annexins are a family of proteins that bind acidic phospholipids in the presence of Ca
2+. The interaction of these proteins with biological membranes has led to the suggestion …

A second, important, difference between the study of regulated exocytosis and the earlier
transport steps is that a significant contribution towards our knowledge of vesicular transport …

3-3 proteins are apparently ubiquitous eukaryotic proteins that comprise a large number of
isoforms. They have been implicated in the regulation of a wide range of biological …

Cyclic AMP regulates the late step of Ca2+-dependent exocytosis in many secretory cells
through two major mechanisms: a protein kinase A-dependent and a cAMP-GEF/Epac …

The ability of individual members of the 14-3-3 protein family to inhibit protein kinase C
(PKC) has been studied by using a synthetic peptide based on the specific 80 kDa substrate …

Cyclic AMP regulates Ca2+‐dependent exocytosis through a classical protein kinase A
(PKA)‐dependent and an alternative cAMP–guanine nucleotide exchange factor …

Various post‐translational modifications (PTMs) regulate the localisation and function of the
multifunctional protein Annexin A2 (AnxA2). In addition to its various tasks as a cytoskeletal …

Isoform-specific antisera were used to examine which 14-3-3 isoforms were present in
bovine adrenal chromaffin cells. The eta, tau and sigma isoforms were not detectable, and …

14‐3‐3 proteins appear to play a critical role in Ca2+‐stimulated secretion in permeabilized
chromaffin cells. 14‐3‐3 proteins have been reported to be both stimulators and inhibitors of …

An abundant cellular and secretory product of isolated seminiferous tubules from adult rats
was identified as having an apparent molecular weight of∼ 24 000 and a pI of 5.3 on …