Over the past 20 years, protein engineering has been extensively used to improve and
modify the fundamental properties of fluorescent proteins (FPs) with the goal of adapting …

Singlet oxygen, O2 (a1Δg), the lowest excited electronic state of molecular oxygen, has
been known to the scientific community for∼ 80 years. It has a characteristic chemistry that …

We review recent advances in laser cell surgery, and investigate the working mechanisms of
femtosecond laser nanoprocessing in biomaterials with oscillator pulses of 80-MHz …

Synapses are often far from the soma and independently cope with proteopathic stress
induced by intense neuronal activity. However, how presynaptic compartments turn over …

We describe a new method for selective cell targeting based on the use of light-absorbing
microparticles and nanoparticles that are heated by short laser pulses to create highly …

Tumour cell invasiveness is crucial for cancer metastasis and is not yet understood. Here we
describe two functional screens for proteins required for the invasion of fibrosarcoma cells …

Abstract Singlet oxygen (1O2) is unique amongst reactive oxygen species formed in cells in
that it is an excited state molecule with an inherent upper lifetime of 4 μs in water. Whether …

Background Invasion is an important early step of cancer metastasis that is not well
understood. Developing therapeutics to limit metastasis requires the identification and …

Optogenetic techniques provide effective ways of manipulating the functions of selected
neurons with light. In the current study, we engineered an optogenetic technique that directly …

Chromophore-assisted light inactivation (CALI) is a powerful technique for acute
perturbation of biomolecules in a spatio-temporally defined manner in living specimen with …