Extracellular vesicles (EVs) can facilitate essential communication among cells in a range of
pathophysiological conditions including cancer metastasis and progression, immune …

Exosomes are membrane-bound nanovesicles secreted by all cell types and contain diverse
molecules. Detecting cancer-derived exosomes and their cargo, which are closely related to …

Rapid and specific quantitation of a variety of RNAs with low expression levels in early-stage
cancer is highly desirable but remains a challenge. Here, we present a dual signal …

The analysis of messenger RNA (mRNA) in extracellular vesicles (EVs) may provide
unprecedented opportunities for non-invasive and rapid diagnosis of cancers. However …

The clustered regularly interspaced short palindromic repeats (CRISPR)/associated
nuclease (Cas) system is an efficient gene editing tool. In this study, it is found that both …

Herein, a simple all-in-one biosensor based on a DNA three-way junction has been
constructed for in situ simultaneous detection of multiple miRNAs by competitive strand …

Exosomes are cell-derived, nanosized extracellular vesicles for intercellular communication.
Exosomal RNAs have been shown as one type of promising cancer liquid biopsy …

The simultaneous detection of proteins and microRNA (miRNA) at the single extracellular
vesicle (EV) level shows great promise for precise disease profiling, owing to the …

Pancreatic cancer (PC) has a poor prognosis due to the lack of effective molecular
biomarkers for early diagnosis. Recent studies have investigated the use of exosomal …

Exosomes are considered as biomarkers reflecting the physiological state of the human
body. Studies have revealed that the expression levels of specific exosomal RNAs are …