Blood-based liquid biopsy: Insights into early detection and clinical management of lung cancer

C Liu, X Xiang, S Han, HY Lim, L Li, X Zhang, Z Ma… - Cancer Letters, 2022 - Elsevier
Currently, early detection of lung cancer relies on the characterisation of images generated
from computed tomography (CT). However, lung tissue biopsy, a highly invasive surgical …

Lung cancer risk prediction with machine learning models

E Dritsas, M Trigka - Big Data and Cognitive Computing, 2022 - mdpi.com
The lungs are the center of breath control and ensure that every cell in the body receives
oxygen. At the same time, they filter the air to prevent the entry of useless substances and …

Configuring therapeutic aspects of immune checkpoints in lung cancer

A Khadela, VP Chavda, H Postwala, R Ephraim… - Cancers, 2023 - mdpi.com
Simple Summary There is a need to improve the conventional treatment options for lung
cancer. Immunotherapy is based on the premise that therapeutic drugs destroy tumor cells …

[Retracted] Adaptive Diagnosis of Lung Cancer by Deep Learning Classification Using Wilcoxon Gain and Generator

O Obulesu, S Kallam, G Dhiman… - Journal of …, 2021 - Wiley Online Library
Cancer is a complicated worldwide health issue with an increasing death rate in recent
years. With the swift blooming of the high throughput technology and several machine …

Activities against lung cancer of biosynthesized silver nanoparticles: a review

JL Mejía-Méndez, ER López-Mena, E Sánchez-Arreola - Biomedicines, 2023 - mdpi.com
Nanomedicine is an interdisciplinary field where nanostructured objects are applied to treat
or diagnose disease. Nanoparticles (NPs) are a special class of materials at nanometric …

Using socio-demographic and early clinical features in general practice to identify people with lung cancer earlier

B Iyen-Omofoman, LJ Tata, DR Baldwin, CJP Smith… - Thorax, 2013 - thorax.bmj.com
Introduction In the UK, most people with lung cancer are diagnosed at a late stage when
curative treatment is not possible. To aid earlier detection, the socio-demographic and early …

Discovery, development, inventions, and patent trends on mobocertinib succinate: The first-in-class oral treatment for NSCLC with EGFR exon 20 insertions

M Imran, SA Khan, MK Alshammari, MA Alreshidi… - Biomedicines, 2021 - mdpi.com
The majority of lung cancers are non-small-cell lung cancer (NSCLC) having a low survival
rate. Recent studies have indicated the involvement of epidermal growth factor receptor …

LncRNA HULC promotes lung squamous cell carcinoma by regulating PTPRO via NF‐κB

Y Xu, J Li, P Wang, Z Zhang… - Journal of Cellular …, 2019 - Wiley Online Library
Accumulating studies have implicated that long noncoding RNA (lncRNA) plays a vital role
in lung cancer. However, little is known of the role of lncRNA highly upregulated in liver …

In silico screening of available drugs targeting non-small cell lung cancer targets: A drug repurposing approach

MK Thirunavukkarasu, U Suriya, T Rungrotmongkol… - Pharmaceutics, 2021 - mdpi.com
The RAS–RAF–MEK–ERK pathway plays a key role in malevolent cell progression in many
tumors. The high structural complexity in the upstream kinases limits the treatment progress …

Knowledge-based mechanistic modeling accurately predicts disease progression with gefitinib in EGFR-mutant lung adenocarcinoma

A L'Hostis, JL Palgen, A Perrillat-Mercerot… - npj Systems Biology …, 2023 - nature.com
Lung adenocarcinoma (LUAD) is associated with a low survival rate at advanced stages.
Although the development of targeted therapies has improved outcomes in LUAD patients …