Rheumatoid arthritis (RA) is an autoimmune inflammatory systematic complication which is a
chronic disorder that severely affects bones and joints and results in the quality of life …

The aim of this study was to prepare and characterize topical methotrexate (MTX) with
different percentages (0.05%, 0.1%, 0.25% and 0.5%) entrapped in deformable liposomes …

Prolonged exposure to the pharmacological doses of disease-modifying anti-rheumatic
drugs (DMARDs) often results in major organ toxicities resulting in poor patient compliance …

Overdosing is the major cause of acute methotrexate toxicity in psoriasis patients. There are
no published data regarding the acute cumulative dose causing acute toxicity, duration to …

Even today methotrexate (MTX) remains the backbone of psoriasis management in
dermatological practice. The widespread usage as well as over the counter availability of …

Methotrexate is an antimetabolite drug with antineoplastic and immunomodulatory
properties, useful as an antineoplastic agent in various haematological and solid tumours …

ABSTRACT Background: Globally, 0.5–1% general population are suffering from
rheumatoid arthritis (RA). RA is a chronic systemic self-immune medicated inflammatory …

Introduction: Pemphigus Vulgaris is a rare, noncommunicable, non-hereditary fatal
autoimmune dermatological manifestation in which a painful blister initiates from the oral …

Acute methotrexate (MTX) toxicity is most commonly due to overdose of the drug, which may
be due to the patient's noncompliance to doctor's orders or physician's prescription error …

We describe two cases of low dose methotrexate (MTX) toxicity in patients with psoriasis.
Patient was a 49-year-old male, known case of chronic plaque psoriasis from 10 years on …