Fancm has dual roles in the limiting of meiotic crossovers and germ cell maintenance in mammals
Meiotic crossovers are required for accurate chromosome segregation and producing new
allelic combinations. Meiotic crossover numbers are tightly regulated within a narrow range …
allelic combinations. Meiotic crossover numbers are tightly regulated within a narrow range …
FANCM Gene Variants in a Male Diagnosed with Sertoli Cell-Only Syndrome and Diffuse Astrocytoma
Azoospermia is a form of male infertility characterized by a complete lack of spermatozoa in
the ejaculate. Sertoli cell-only syndrome (SCOS) is the most severe form of azoospermia …
the ejaculate. Sertoli cell-only syndrome (SCOS) is the most severe form of azoospermia …
Myelodysplastic syndrome and multiple solid tumours in an individual with compound heterozygous deleterious FANCM variants: A case report and review of the …
JY Ng, L Warwick, P Craft, L Austen… - British Journal of …, 2023 - search.ebscohost.com
Most cases reported chemotherapy and radiotherapy toxicities including myelosuppression,
and mucositis. Individuals with FANCM biallelic mutations do not develop Fanconi anemia …
and mucositis. Individuals with FANCM biallelic mutations do not develop Fanconi anemia …
Grade 5 Radiation Necrosis After Whole-Brain Radiation Therapy
A Tam, YR Li, T Williams, S Yoon - Practical Radiation Oncology, 2024 - Elsevier
Whole-brain radiation treatment is often considered for patients with leptomeningeal
disease. There are limited reports of the development of radiation necrosis after whole-brain …
disease. There are limited reports of the development of radiation necrosis after whole-brain …
Fancm regulates meiotic double-strand break repair pathway choice in mammals
V Tsui, R Lyu, S Novakovic, JM Stringer, JEM Dunleavy… - bioRxiv, 2022 - biorxiv.org
Meiotic crossovers are required for accurate chromosome segregation and to produce new
allelic combinations. Meiotic crossover numbers are tightly regulated within a narrow range …
allelic combinations. Meiotic crossover numbers are tightly regulated within a narrow range …
[PDF][PDF] Homozygous FANCM variant c. 5101C> T p.(Gln1701*) in a patient with early onset breast cancer, chemotherapy toxicity, and chromosome fragility
S Sulkava, AH Hakonen, M Pöyhönen… - Authorea …, 2024 - authorea.com
Homozygous FANCM variant c. 5101C> T p.(Gln1701*) in a patient with early onset breast
cancer, chemotherapy toxicity, and chromosome fragilitySonja Sulkava1, 2*, Anna H …
cancer, chemotherapy toxicity, and chromosome fragilitySonja Sulkava1, 2*, Anna H …