Botulinum toxin intervention in cerebral palsy-induced spasticity management: projected and contradictory effects on skeletal muscles

CS Kaya Keles, F Ates - Toxins, 2022 - mdpi.com
Spasticity, following the neurological disorder of cerebral palsy (CP), describes a
pathological condition, the central feature of which is involuntary and prolonged muscle …

[HTML][HTML] Botulinum toxin intervention in cerebral palsy-induced spasticity management: projected and contradictory effects on skeletal muscles

CSK Keles, F Ates - Toxins, 2022 - ncbi.nlm.nih.gov
Spasticity, following the neurological disorder of cerebral palsy (CP), describes a
pathological condition, the central feature of which is involuntary and prolonged muscle …

Changes in contractile properties of muscles receiving repeat injections of botulinum toxin (Botox)

R Fortuna, MA Vaz, AR Youssef, D Longino… - Journal of …, 2011 - Elsevier
Botulinum toxin type A (BTX-A) is a frequently used therapeutic tool to denervate muscles in
the treatment of neuromuscular disorders. Although considered safe by the US Food and …

Botulism

EA Johnson, C Montecucco - Handbook of clinical neurology, 2008 - Elsevier
Publisher Summary Botulism is an acute neuroparalytic disease of humans and animals
caused through the action of botulinum neurotoxins (BoNTs) acting at the neuromuscular …

Botulinum toxin in masticatory muscles: short-and long-term effects on muscle, bone, and craniofacial function in adult rabbits

KL Rafferty, ZJ Liu, W Ye, AL Navarrete, TT Nguyen… - Bone, 2012 - Elsevier
Paralysis of the masticatory muscles using botulinum toxin (BTX) is a common treatment for
cosmetic reduction of the masseters as well as for conditions involving muscle spasm and …

[HTML][HTML] Injection of high dose botulinum-toxin A leads to impaired skeletal muscle function and damage of the fibrilar and non-fibrilar structures

J Pingel, MS Nielsen, T Lauridsen, K Rix, M Bech… - Scientific reports, 2017 - nature.com
Abstract Botulinum-toxin A (BoNT/A) is used for a wide range of conditions. Intramuscular
administration of BoNT/A inhibits the release of acetylcholine at the neuromuscular junction …

Over 25 years of pediatric botulinum toxin treatments: what have we learned from injection techniques, doses, dilutions, and recovery of repeated injections?

H Sätilä - Toxins, 2020 - mdpi.com
Botulinum toxin type A (BTXA) has been used for over 25 years in the management of
pediatric lower and upper limb hypertonia, with the first reports in 1993. The most common …

[HTML][HTML] Muscle structure and stiffness assessment after botulinum toxin type A injection. A systematic review

L Mathevon, F Michel, P Decavel, B Fernandez… - Annals of physical and …, 2015 - Elsevier
Background Botulinum toxin type A manages spasticity disorders in neurological central
diseases. Some studies have reported that it might induce muscle changes. Methods We …

How do the botulinum neurotoxins block neurotransmitter release: from botulism to the molecular mechanism of action

B Poulain, MR Popoff, J Molgó - The Botulinum Journal, 2008 - inderscienceonline.com
An overall picture of the botulinum toxins is provided, linking the recent developments in
their molecular and cellular aspects to the physiological actions. The pathophysiological …

Dramatic changes in muscle contractile and structural properties after 2 botulinum toxin injections

VB Minamoto, KP Suzuki, SN Bremner… - Muscle & …, 2015 - Wiley Online Library
Introduction: Botulinum toxin is frequently administered serially to maintain therapeutic
muscle paralysis, but the effect of repeated doses on muscle function are largely unknown …