GDF15 has recently gained scientific and translational prominence with the discovery that its
receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain …

Obesity is a complex disorder of excessive adiposity, and is associated with adverse health
effects such as cardiometabolic complications, which are to a large extent attributable to …

Oxygen deprivation can be detrimental. However, chronic hypoxia is also associated with
decreased incidence of metabolic syndrome and cardiovascular disease in high-altitude …

Background There are few data on the clinical outcomes of patients with coronavirus
disease 2019 (COVID-19) in cities over 1000 m above sea level (masl). Objectives To …

The use of exercise intervention in hypoxia has grown in popularity amongst patients, with
encouraging results compared to similar intervention in normoxia. The prescription of …

Aim The aim of the present study was to examine the effect of exercise intervention in
hypoxia as a novel treatment method for obesity in older men. Methods A total of 24 obese …

Introduction: Worldwide, more than 5.7% of the population reside above 1,500 m of
elevation. It has been hypothesized that acute short-term hypoxia exposure could increase …

Obesity is an important health problem caused by positive energy balance. Generally, low
calorie dietary intake combined with regular exercise is the most common modality to lose …

Dietary pattern is quite distinct among the inhabitants of high-altitude areas because of
environmental and geographical uniqueness; hence, it is important to investigate this data …

Obesity is a significant public health concern in the United States. The relationship between
recreational opportunity and health conditions have been examined at an individual level by …