Simple Summary In this review, we present a detailed discussion of how the plasminogen-
activation system is utilized by tumor cells in their unrelenting attack on the tissues …

Background: Metastatic melanoma stands out as the most lethal form of skin cancer because
of its high propensity to spread and its remarkable resistance to treatment methods …

Purpose In this research, we analyzed the expression of serpinB9 in hepatoblastoma and
investigated the factors which enhance its expression. Method SerpinB9 expression in …

Background Oral squamous cell carcinoma (OSCC) has increased in incidence from 1990 to
2017, especially in South and Southeast Asia. It is often diagnosed at an advanced stage …

Background The infiltrative nature of human gliomas renders complete surgical removal of
tumors futile. Thus, illuminating mechanisms of their infiltrative properties may improve …

COVID-19 outbreak is the biggest threat to human health in recent history. Currently, there
are over 1.5 million related deaths and 75 million people infected around the world (as of …

Serine hydrolases play crucial roles in many physiological and pathophysiological
processes and a panel of these enzymes are targets of approved drugs. Despite this, most of …

In the present study, a series of L-valine derived boroxazolidones, previously synthesized
and reported to have residual activity in a human epithelial cell line, have been evaluated in …

Lumbrokinases (LKs) belong to the group serine proteases capable to prevent thrombosis
through the proteolysis of both plasminogen-bound and plasminogen-free fibrin molecules …

The growing world population comes with a serious concern on how to sustainably meet the
people's nutritional demand now and for the generations to come. The double burden of …