Structural changes upon membrane insertion of the insecticidal pore-forming toxins produced by Bacillus thuringiensis

S Pacheco, I Gómez, AE Peláez-Aguilar… - Frontiers in Insect …, 2023 - frontiersin.org
Different Bacillus thuringiensis (Bt) strains produce a broad variety of pore-forming toxins
(PFTs) that show toxicity against insects and other invertebrates. Some of these insecticidal …

A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst

R Schönherr, J Boger, JM Lahey-Rudolph… - Nature …, 2024 - nature.com
With the advent of serial X-ray crystallography on microfocus beamlines at free-electron
laser and synchrotron facilities, the demand for protein microcrystals has significantly risen …

[HTML][HTML] Structural and Functional Insights into the Delivery Systems of Bacillus and Clostridial Binary Toxins

SE Sevdalis, KM Varney, ME Cook, JJ Gillespie… - Toxins, 2024 - mdpi.com
Pathogenic Bacillus and clostridial (ie, Clostridium and Clostridioides) bacteria express a
diverse repertoire of effector proteins to promote disease. This includes production of binary …

Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX

LJ Williamson, M Galchenkova… - Proceedings of the …, 2023 - National Acad Sciences
The Lysinibacillus sphaericus proteins Tpp49Aa1 and Cry48Aa1 can together act as a toxin
toward the mosquito Culex quinquefasciatus and have potential use in biocontrol. Given that …

Purification, characterization and proteolytic processing of mosquito larvicidal protein Cry11Aa from Bacillus thuringiensis subsp. israelensis ISPC-12

OU Kinkar, A Prashar, B Yadav, A Kumar… - International Journal of …, 2023 - Elsevier
Cry11Aa is the most potent mosquito larvicidal protein of Bacillus thuringiensis subsp.
israelensis (Bti). Development of resistance against insecticidal proteins including Cry11Aa …

Channel Formation in Cry Toxins: An Alphafold-2 Perspective

J Torres, W Surya, P Boonserm - International journal of molecular …, 2023 - mdpi.com
Bacillus thuringiensis (Bt) strains produce pore-forming toxins (PFTs) that attack insect pests.
Information for pre-pore and pore structures of some of these Bt toxins is available. However …

苏云金芽孢杆菌晶体蛋白结构及其机制的研究进展.

张也, 臧传, 刘宏美 - China Tropical Medicine, 2023 - search.ebscohost.com
山东省寄生虫病防治研究所, 山东第一医科大学(山东省医学科学院), 山东济宁272033 摘要:
蚊虫作为媒介参与疟疾, 登革热, 基孔肯雅热, 黄热病, 寨卡和丝虫病等严重疾病的传播 …

One touch is all it takes: the supramolecular interaction between ubiquitin and lanthanide complexes revisited by paramagnetic NMR and molecular dynamics

K Dos Santos, A Bartocci, N Gillet… - Physical Chemistry …, 2024 - pubs.rsc.org
The supramolecular interaction between lanthanide complexes and proteins is at the heart
of numerous chemical and biological studies. Some of these complexes have demonstrated …

A snapshot love story: what serial crystallography has done and will do for us

A Henkel, D Oberthür - Biological Crystallography, 2024 - journals.iucr.org
Serial crystallography, born from groundbreaking experiments at the Linac Coherent Light
Source in 2009, has evolved into a pivotal technique in structural biology. Initially pioneered …

The Perpetual Vector Mosquito Threat and Its Eco-Friendly Nemeses

LS Miranda, SR Rudd, O Mena, PE Hudspeth… - Biology, 2024 - mdpi.com
Simple Summary Aedes, Culex, and Anopheles mosquitoes are the most prolific arthropod
vectors of viral and parasitic agents of debilitating and lethal diseases in humans and …