Estimating the prevalence of heterozygous familial hypercholesterolaemia: a systematic review and meta-analysis

LE Akioyamen, J Genest, SD Shan, RL Reel… - BMJ open, 2017 - bmjopen.bmj.com
Objectives Heterozygous familial hypercholesterolaemia (FH) confers a significant risk for
premature cardiovascular disease (CVD). However, the estimated prevalence of FH varies …

2023 Chinese guideline for lipid management

JJ Li, SP Zhao, D Zhao, GP Lu, DQ Peng… - Frontiers in …, 2023 - frontiersin.org
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death among urban
and rural residents in China, and elevated low-density lipoprotein cholesterol (LDL-C) is a …

Familial hypercholesterolaemia: evolving knowledge for designing adaptive models of care

GF Watts, SS Gidding, P Mata, J Pang… - Nature Reviews …, 2020 - nature.com
Optimal care for familial hypercholesterolaemia (FH) requires patient-centred management,
multidisciplinary teamwork, involvement of primary care practitioners, patient networks …

Genetically confirmed familial hypercholesterolemia in patients with acute coronary syndrome

A Amor-Salamanca, S Castillo… - Journal of the American …, 2017 - jacc.org
Background: Genetic screening programs in unselected individuals with increased levels of
low-density lipoprotein cholesterol (LDL-C) have shown modest results in identifying …

Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia

M Paquette, M Chong, S Thériault, R Dufour… - Journal of clinical …, 2017 - Elsevier
Background Although familial hypercholesterolemia (FH) is a severe monogenic disease, it
has been shown that clinical risk factors and common genetic variants can modify …

The role of artificial intelligence in hypertensive disorders of pregnancy: towards personalized healthcare

M Alkhodari, Z Xiong, AH Khandoker… - Expert Review of …, 2023 - Taylor & Francis
Introduction Guidelines advise ongoing follow-up of patients after hypertensive disorders of
pregnancy (HDP) to assess cardiovascular risk and manage future patient-specific …

Alirocumab in pediatric patients with heterozygous familial hypercholesterolemia: a randomized clinical trial

RD Santos, A Wiegman, S Caprio, B Cariou… - JAMA …, 2024 - jamanetwork.com
Importance Many pediatric patients with heterozygous familial hypercholesterolemia (HeFH)
cannot reach recommended low-density lipoprotein cholesterol (LDL-C) concentrations on …

[HTML][HTML] 2023 China guidelines for lipid management

LI Jian-Jun, Z Shui-Ping, Z Dong… - Journal of Geriatric …, 2023 - ncbi.nlm.nih.gov
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death among urban
and rural residents in China, and elevated low-density lipoprotein cholesterol (LDL-C) is a …

Risk factors for cardiovascular disease in heterozygous familial hypercholesterolemia: A systematic review and meta-analysis

LE Akioyamen, J Genest, A Chu, H Inibhunu… - Journal of clinical …, 2019 - Elsevier
Background Current data from individual studies present conflicting evidence about the
relationship between risk factors and cardiovascular disease (CVD) in heterozygous familial …

Universal screening at age 1–2 years as an adjunct to cascade testing for familial hypercholesterolaemia in the UK: a cost-utility analysis

AJ McKay, H Hogan, SE Humphries, D Marks, KK Ray… - Atherosclerosis, 2018 - Elsevier
Background and aims Familial hypercholesterolaemia (FH) is widely underdiagnosed.
Cascade testing (CT) of relatives has been shown to be feasible, acceptable and cost …