Importance Intracranial metastatic disease (IMD) is a severe complication of cancer with
profound prognostic implications. Patients with IMD in the setting of limited or stable …

Background We performed an updated meta-analysis to explore the value of locoregional
surgery in de novo stage IV breast cancer patients. Methods A literature search was …

Whether patients with de novo metastatic breast cancer (de novo MBC) benefit from primary
tumor resection (PTR) is controversial, and the efficacy of treatment of primary tumor in …

Background Brain is a common metastasis site in lung cancer patients. However,
homogeneous and heterogeneous risk/prognostic factors of brain metastasis for lung cancer …

Background We previously reported survival benefit of surgery in patients with stage IV
breast cancer (BC); prospective trials yielded inconclusive results. Methods We sampled the …

Purpose Locoregional therapy at primary or secondary sites in breast cancer may be
associated with improved survival as compared to systemic therapy alone. We explored the …

Background Metastasectomy is a useful adjunct in the management of metastatic cancer.
Widespread adoption of novel targeted and immunotherapies has improved the survival …

Background & objectives An effective tool for forecasting the survival of BCLM is lacking.
This study aims to construct nomograms to predict overall survival (OS) and breast cancer …

This study aimed to evaluate whether palliative surgery for metastatic lesion could provide a
survival benefit in metastatic breast cancer (MBC) patients with solitary metastasis. De novo …

Background/Aim: The lymph node ratio (LNR) indicates the number of involved lymph nodes
divided by the number of lymph nodes found during axillary exploration. This study …