Pharmacological overview of hederagenin and its derivatives

X Huang, QK Shen, HY Guo, X Li… - RSC Medicinal Chemistry, 2023 - pubs.rsc.org
Hederagenin is a pentacyclic triterpenoid isolated from plants and widely distributed in a
variety of medicinal plants. By integrating and analyzing external related literature reports …

Nanotechnology-based topical delivery of natural products for the management of atopic dermatitis

MP Marques, C Varela, L Mendonça, C Cabral - Pharmaceutics, 2023 - mdpi.com
Atopic dermatitis (AD) is a chronic eczematous inflammatory disease that may arise from
environmental, genetic, and immunological factors. Despite the efficacy of current treatment …

Transdermal delivery of natural products against atopic dermatitis

LI Minghui, XU Yihua, YU Yanan, LI Wanshu… - Chinese Journal of …, 2024 - Elsevier
Atopic dermatitis (AD) is a chronic inflammatory skin condition. Natural products have
gained traction in AD treatment due to their accessibility, low toxicity, and favorable …

The applications of functional materials-based nano-formulations in the prevention, diagnosis and treatment of chronic inflammation-related diseases

J Wang, R Ni, T Jiang, D Peng, Y Ming… - Frontiers in …, 2023 - frontiersin.org
Chronic inflammation, in general, refers to systemic immune abnormalities most often
caused by the environment or lifestyle, which is the basis for various skin diseases …

An updated review of the pharmacological effects and potential mechanisms of hederagenin and its derivatives

H Zhang, Y Li, Y Liu - Frontiers in Pharmacology, 2024 - frontiersin.org
Hederagenin (HG) is a natural pentacyclic triterpenoid that can be isolated from various
medicinal herbs. By modifying the structure of HG, multiple derivatives with superior …

Hederagenol improves multiple sclerosis by modulating Th17 cell differentiation

D Guan, Y Li, X Zhao, K Wang, Y Guo, N Dong… - IUBMB …, 2024 - Wiley Online Library
Multiple sclerosis (MS) is a common autoimmune illness that is difficult to treat. The
upregulation of Th17 cells is critical in the pathological process of MS. Hederagenol (Hed) …

Yu-Ping-Feng-San alleviates inflammation in atopic dermatitis mice by TLR4/MyD88/NF-κB pathway

J Nie, X Jiang, G Wang, Y Xu, R Pan, W Yu, Y Li… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Yu-Ping-Feng-San (YPF) is a traditional Chinese
medicine formula that has therapeutic effects on allergic diseases such as allergic rhinitis …

[HTML][HTML] Extracts of Grifola frondosa inhibit the MAPK signaling pathways involved in keratinocyte inflammation and ameliorate atopic dermatitis

EJ Choi, JK Choi - Nutrition Research and Practice, 2023 - ncbi.nlm.nih.gov
RESULTS Our study revealed that G. frondosa ameliorates clinical symptoms in an AD-like
mouse model. These effects contributed to the suppression of Th1, Th2, Th17, and Th22 …

[HTML][HTML] A Novel Facial Cream Based on Skin Penetrable Hemp Oil Microparticles

R Lubart, I Yariv, D Fixler, A Rothstein… - Journal of Cosmetics …, 2023 - scirp.org
Objective: Hemp seed oil is perfect for most skin types; it moisturizes skin and protects it from
inflammation, oxidation, and other causes of aging. The problem is that the Hemp oil-based …