GABA A receptors are the major inhibitory transmitter receptors in the brain. They are ligand-
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …

Cl− channels reside both in the plasma membrane and in intracellular organelles. Their
functions range from ion homeostasis to cell volume regulation, transepithelial transport, and …

GABAA receptors are ligand-operated chloride channels assembled from five subunits in a
heteropentameric manner. Using immunocytochemistry, we investigated the distribution of …

γ-Aminobutyrate (GABA) is a major inhibitory neurotransmitter in the adult mammalian brain.
GABA is also considered to be a multifunctional molecule that has different situational …

The two amino acids GABA and glycine mediate fast inhibitory neurotransmission in different
CNS areas and serve pivotal roles in the spinal sensory processing. Under healthy …

The amino acid γ-aminobutyric-acid (GABA) prevails in the CNS as an inhibitory neurotrans-
mitter that mediates most of its effects through fast GABA-gated Cl−-channels (GABA AR) …

In an effort to determine subunit compositions of in vivo GABAA receptors, the cellular
localization of 13 subunit encoding mRNAs (alpha 1-alpha 6, beta 1-beta 3, gamma 2 …

Recent advances in molecular biology and complementary information derived from
neuropharmacology, biochemistry and behavior have dramatically increased our …

The genes of the ionotropic γ-aminobutyric acid receptor (GABR) subunits have shown an
unusual chromosomal clustering, but only now can this be fully specified by analyses of the …

The γ‐aminobutyric acid type A (GABAA) receptor represents an elementary switching
mechanism integral to the functioning of the central nervous system and a locus for the …