Histone deacetylase complexes: Structure, regulation and function
MD Asmamaw, A He, LR Zhang, HM Liu… - Biochimica et Biophysica …, 2024 - Elsevier
Histone deacetylases (HDACs) are key epigenetic regulators, and transcriptional complexes
with deacetylase function are among the epigenetic corepressor complexes in the nucleus …
with deacetylase function are among the epigenetic corepressor complexes in the nucleus …
The chromatin signatures of enhancers and their dynamic regulation
A Barral, J Déjardin - Nucleus, 2023 - Taylor & Francis
Enhancers are cis-regulatory elements that can stimulate gene expression from distance,
and drive precise spatiotemporal gene expression profiles during development. Functional …
and drive precise spatiotemporal gene expression profiles during development. Functional …
Alternative mRNA splicing controls the functions of the histone H3K27 demethylase UTX/KDM6A
Simple Summary UTX/KDM6A is a histone H3K27 demethylase and plays an important role
in mammalian development and human diseases such as urothelial cancer. We identified a …
in mammalian development and human diseases such as urothelial cancer. We identified a …
Mitotic deacetylase complex (MiDAC) recognizes the HIV-1 core promoter to control activated viral gene expression
E Wilhelm, M Poirier, M Da Rocha, M Bédard… - Plos …, 2024 - journals.plos.org
The human immunodeficiency virus (HIV) integrates into the host genome forming latent
cellular reservoirs that are an obstacle for cure or remission strategies. Viral transcription is …
cellular reservoirs that are an obstacle for cure or remission strategies. Viral transcription is …
ELM2‐SANT Domain‐Containing Scaffolding Protein 1 Regulates Differentiation and Maturation of Cardiomyocytes Derived From Human‐Induced Pluripotent Stem …
Background ELMSAN1 (ELM2‐SANT domain‐containing scaffolding protein 1) is a newly
identified scaffolding protein of the MiDAC (mitotic deacetylase complex), playing a pivotal …
identified scaffolding protein of the MiDAC (mitotic deacetylase complex), playing a pivotal …
Mitotic deacetylase complex (MiDAC) recognizes the HIV-1 core promoter to control Tat-activated transcription and latency
E Wilhelm, M Poirier, M Bédard, PP McDonald… - bioRxiv, 2023 - biorxiv.org
The human immunodeficiency virus (HIV) integrates into the host genome forming latent
cellular reservoirs that are an obstacle for cure or remission strategies. Viral transcription is …
cellular reservoirs that are an obstacle for cure or remission strategies. Viral transcription is …