[HTML][HTML] A Role of Inflammation in Charcot–Marie–Tooth Disorders—In a Perspective of Treatment?

J Kamińska, A Kochański - International Journal of Molecular Sciences, 2024 - mdpi.com
Despite the fact that there are published case reports and model work providing evidence of
inflammation in Charcot–Marie–Tooth disorders (CMTs), in clinical practice, CMT and …

Alterations in cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation

M Momoh, S Rathan-Kumar… - American Journal …, 2024 - journals.physiology.org
Functional loss of the motor protein myosin Vb (MYO5B) induces various defects in intestinal
epithelial function and causes a congenital diarrheal disorder, namely, microvillus inclusion …

Rab11 and its role in neurodegenerative diseases

P Sultana, J Novotny - ASN neuro, 2022 - journals.sagepub.com
Vesicles mediate the trafficking of membranes/proteins in the endocytic and secretory
pathways. These pathways are regulated by small GTPases of the Rab family. Rab proteins …

[HTML][HTML] Cohort expansion and genotype-phenotype analysis of RAB11A-associated neurodevelopmental disorder

MC Borroto, H Patel, S Srivastava, LC Swanson… - Pediatric …, 2024 - Elsevier
Abstract Background GTPases of the Rab family are important orchestrators of membrane
trafficking, and their dysregulation has been linked to a variety of neuropathologies. In 2017 …

Insights and implications for transcriptomic analysis of heat stress-induced intestinal inflammation in pigs

Z Yu, Y Yong, X Liu, X Ma, AM Abd El-Aty, L Li, Z Zhong… - BMC genomics, 2024 - Springer
Background Heat stress (HS) can affect the physiology and metabolism of animals. HS-
induced intestinal inflammation in pigs is a common disease, causing severe diarrhea, that …

Electrospun mini-MiSp spidroin/poly (L-lactide-co-ε-caprolactone) nanofibrous scaffolds for ARPE-19 cells

C Liu, K Yi, Z Zhang, Q Li, H Li, C Qu… - Biotechnology & …, 2023 - Taylor & Francis
Age-related macular degeneration, a type of retinal degenerative disease, is the primary
cause of severe visual impairment and irreversible blindness in people older than 50, due to …

Altered cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation

M Momoh, S Rathan-Kumar, A Burman, ME Brown… - bioRxiv, 2024 - biorxiv.org
Functional loss of the motor protein, Myosin Vb (MYO5B), induces various defects in
intestinal epithelial function and causes a congenital diarrheal disorder, microvillus inclusion …

The Identification of Key Genes and Biological Pathways in Cardiac Arrest by Integrated Bioinformatics and Next Generation Sequencing Data Analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Cardiac arrest (CA) is a common cause of death world wide. The disease has lacks effective
treatment. Efforts have been made to elucidate the molecular pathogenesis of CA, but the …

[PDF][PDF] Investigating the Role of the Pseudokinase IRAK-3 in Signalling by Toll-Like Receptors

C Aitken - 2024 - discovery.dundee.ac.uk
The immune system of an organism is a collection of processes that protect it against
disease. The mammalian immune system is comprised of two branches, namely the innate …