The exercise pressor reflex is a feedback mechanism engaged upon stimulation of mechano-
and metabosensitive skeletal muscle afferents. Activation of these afferents elicits a reflex …

Autonomic alterations at the onset of exercise are critical to redistribute cardiac output
towards the contracting muscles while preventing a fall in arterial pressure due to excessive …

Introduction: Prior studies report conflicting evidence regarding exercise pressor and
metaboreflex responses in individuals with metabolic syndrome (MetS). Purpose: To test the …

Stimulation of mechanically sensitive channels on the sensory endings of group III and IV
thin fiber muscle afferents activates the mechanoreflex, which contributes to reflex increases …

Autonomic adjustments of the cardiovascular system are critical for initiating and sustaining
exercise by facilitating the redistribution of blood flow and oxygen delivery to meet the …

The blood pressure response to exercise is exaggerated in type 2 diabetes (T2D). However,
the underlying mechanisms remain unclear. It is hypothesized that one mechanism …

Patients with heart failure with reduced (HFrEF) and preserved ejection fraction (HFpEF)
exhibit severe exercise intolerance that may be due, in part, to inappropriate cardiovascular …

Type 2 diabetes mellitus (T2DM) leads to exaggerated cardiovascular responses to
exercise, in part due to an exaggerated exercise pressor reflex. Accumulating data suggest …

Introduction: Studies in humans and animals have found that type 2 diabetes mellitus
(T2DM) exaggerates the blood pressure (BP) response to exercise, which increases the risk …

Mechanical and metabolic signals associated with skeletal muscle contraction stimulate the
sensory endings of thin fiber muscle afferents and produce reflex increases in sympathetic …