The development of the endoderm is a multistage process. From the initial specification of the endodermal domain in the embryo to the final regionalization of the gut, there are …
Identifying the molecular fingerprint of organismal cell types is key for understanding their function and evolution. Here, we use single-cell RNA sequencing (scRNA-seq) to survey the …
S Grainger, JGA Savory, D Lohnes - Developmental biology, 2010 - Elsevier
Cdx1, Cdx2 and Cdx4 encode homeodomain transcription factors that are involved in vertebral anterior–posterior (AP) patterning. Cdx1 and Cdx2 are also expressed in the …
Using scRNA-seq coupled with computational approaches, we studied transcriptional changes in cell states of sea urchin embryos during development to the larval stage …
P Paganos, P Ronchi, J Carl, G Mizzon… - Frontiers in cell and …, 2022 - frontiersin.org
The identity and function of a given cell type relies on the differential expression of gene batteries that promote diverse phenotypes and functional specificities. Therefore, the …
Echinoderms are a phylum of invertebrate deuterostomes that are morphologically characterized by a fivefold (pentameric) symmetric adult body plan. There are five extant …
The emergence of a specialized system for food digestion and nutrient absorption was a crucial innovation for multicellular organisms. Digestive systems with different levels of …
Background In sea urchin larvae the circumesophageal fibers form a prominent muscle system of mesodermal origin. Although the morphology and later development of this …
Identifying the location of a specific RNA in a cell, tissue, or embryo is essential to understand its function. Here we use echinoderm embryos to demonstrate the power of …