Vertebrate intestinal endoderm development

JR Spence, R Lauf, NF Shroyer - Developmental dynamics, 2011 - Wiley Online Library
The endoderm gives rise to the lining of the esophagus, stomach and intestines, as well as
associated organs. To generate a functional intestine, a series of highly orchestrated …

Pattern and process during sea urchin gut morphogenesis: the regulatory landscape

R Annunziata, M Perillo, C Andrikou, AG Cole… - genesis, 2014 - Wiley Online Library
The development of the endoderm is a multistage process. From the initial specification of
the endodermal domain in the embryo to the final regionalization of the gut, there are …

Single-cell RNA sequencing of the Strongylocentrotus purpuratus larva reveals the blueprint of major cell types and nervous system of a non-chordate deuterostome

P Paganos, D Voronov, JM Musser, D Arendt… - Elife, 2021 - elifesciences.org
Identifying the molecular fingerprint of organismal cell types is key for understanding their
function and evolution. Here, we use single-cell RNA sequencing (scRNA-seq) to survey the …

[HTML][HTML] Cdx2 regulates patterning of the intestinal epithelium

S Grainger, JGA Savory, D Lohnes - Developmental biology, 2010 - Elsevier
Cdx1, Cdx2 and Cdx4 encode homeodomain transcription factors that are involved in
vertebral anterior–posterior (AP) patterning. Cdx1 and Cdx2 are also expressed in the …

Developmental single-cell transcriptomics in the Lytechinus variegatus sea urchin embryo

AJ Massri, L Greenstreet, A Afanassiev… - …, 2021 - journals.biologists.com
Using scRNA-seq coupled with computational approaches, we studied transcriptional
changes in cell states of sea urchin embryos during development to the larval stage …

Integrating single cell transcriptomics and volume electron microscopy confirms the presence of pancreatic acinar-like cells in sea urchins

P Paganos, P Ronchi, J Carl, G Mizzon… - Frontiers in cell and …, 2022 - frontiersin.org
The identity and function of a given cell type relies on the differential expression of gene
batteries that promote diverse phenotypes and functional specificities. Therefore, the …

Echinodermata

MI Arnone, M Byrne, P Martinez - Evolutionary developmental biology of …, 2015 - Springer
Echinoderms are a phylum of invertebrate deuterostomes that are morphologically
characterized by a fivefold (pentameric) symmetric adult body plan. There are five extant …

Development and evolution of gut structures: from molecules to function

R Annunziata, C Andrikou, M Perillo, C Cuomo… - Cell and tissue …, 2019 - Springer
The emergence of a specialized system for food digestion and nutrient absorption was a
crucial innovation for multicellular organisms. Digestive systems with different levels of …

Myogenesis in the sea urchin embryo: the molecular fingerprint of the myoblast precursors

C Andrikou, E Iovene, F Rizzo, P Oliveri, MI Arnone - Evodevo, 2013 - Springer
Background In sea urchin larvae the circumesophageal fibers form a prominent muscle
system of mesodermal origin. Although the morphology and later development of this …

Methodology for whole mount and fluorescent RNA in situ hybridization in echinoderms: single, double, and beyond

M Perillo, P Paganos, M Spurrell, MI Arnone… - … Biology of the Sea …, 2021 - Springer
Identifying the location of a specific RNA in a cell, tissue, or embryo is essential to
understand its function. Here we use echinoderm embryos to demonstrate the power of …