Congenital aniridia is a rare genetic eye disorder with total or partial absence of the iris from
birth. In most cases the genetic origin of aniridia is a mutation in the PAX6 gene, leading to …

There is a number of systemic diseases affecting the cornea. These include endocrine
disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections …

Childhood glaucoma represents a heterogenous group of rare ocular conditions that may
result in significant sight threatening complications related to elevated intraocular pressure …

Congenital aniridia is a panocular disorder that is typically characterized by iris hypoplasia
and aniridia-associated keratopathy (AAK). AAK results in the progressive loss of corneal …

Aniridia is most commonly caused by haploinsufficiency of the PAX6 gene, characterized by
variable iris and foveal hypoplasia, nystagmus, cataracts, glaucoma, and aniridia-related …

Purpose To propose an optimized microsurgical and medical approach to reduce the risk of
complications after penetrating keratoplasty (PKP) in patients with aniridia-associated …

The protective function and transparency provided by the corneal epithelium are dependent
on and maintained by the regenerative capacity of limbal epithelial stem cells (LESCs) …

Monogenic syndromic disorders frequently feature ocular manifestations, one of which is
glaucoma. In many cases, glaucoma in children may go undetected, especially in those that …

Background Evaluate outcomes and identify prognostic factors in congenital aniridia.
Methods Retrospective interventional case series of patients with congenital aniridia treated …

Congenital aniridia is a rare, panocular disorder with a main phenotypic characteristic of a
partial or complete absence of the iris existing alongside other ocular morbidities such as …