Revisiting the oxidation of flavonoids: Loss, conservation or enhancement of their antioxidant properties

H Speisky, F Shahidi, A Costa de Camargo, J Fuentes - Antioxidants, 2022 - mdpi.com
Flavonoids display a broad range of health-promoting bioactivities. Among these, their
capacity to act as antioxidants has remained most prominent. The canonical reactive oxygen …

Resveratrol and inflammatory bowel disease: The evidence so far

S Nunes, F Danesi, D Del Rio, P Silva - Nutrition research reviews, 2018 - cambridge.org
Despite the fact that inflammatory bowel disease (IBD) has still no recognised therapy,
treatments which have proven at least mildly successful in improving IBD symptoms include …

Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages

Y Hu, Z Gui, Y Zhou, L Xia, K Lin, Y Xu - Free Radical Biology and …, 2019 - Elsevier
Osteoarthritis (OA) is a progressive joint disorder that is primarily characterized by the
degeneration and destruction of the articular cartilage. Cartilage matrix degradation …

Life or death: neuroprotective and anticancer effects of quercetin

F Dajas - Journal of ethnopharmacology, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Quercetin is a ubiquitous flavonoid that is
present in numerous plants that are utilized in many different cultures for their nervous …

Quercetin and the mitochondria: a mechanistic view

MR de Oliveira, SM Nabavi, N Braidy, WN Setzer… - Biotechnology …, 2016 - Elsevier
Quercetin is an important flavonoid that is ubiquitously present in the diet in a variety of fruits
and vegetables. It has been traditionally viewed as a potent antioxidant and anti …

Polyphenols and mitochondria: an update on their increasingly emerging ROS-scavenging independent actions

C Sandoval-Acuña, J Ferreira, H Speisky - Archives of biochemistry and …, 2014 - Elsevier
Polyphenols, ubiquitously present in fruits and vegetables, have been traditionally viewed
as antioxidant molecules. Such contention emerged, mainly from their well established in …

Alzheimer's disease and the microbiome

S Bhattacharjee, WJ Lukiw - Frontiers in cellular neuroscience, 2013 - frontiersin.org
The recognition of the human microbiome (HM) as a substantial contributor to nutrition,
health and disease is a relatively recent one, and currently, peerreviewed studies linking …

Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid

H Hosseinzadeh, M Nassiri-Asl - Journal of endocrinological investigation, 2014 - Springer
Background In recent years, flavonoids have been revealed to be helpful in the treatment of
many diseases. Rutin (3, 3′, 4′, 5, 7-pentahydroxyflavone-3-rhamnoglucoside) is an …

Effects of supplementation of medium with different antioxidants during in vitro maturation of bovine oocytes on subsequent embryo production

TC Sovernigo, PR Adona, PS Monzani… - … in Domestic Animals, 2017 - Wiley Online Library
Contents The aim of this study was to assess the effects of different antioxidants on the
levels of reactive oxygen species (ROS) and glutathione (GSH) in oocytes during in vitro …

Evolution of phenolic compounds from color and flavor problems to health benefits

A Soto-Vaca, A Gutierrez, JN Losso, Z Xu… - Journal of agricultural …, 2012 - ACS Publications
Early studies focused on the negative effects on color and flavor of foods, followed by
exploration of the antioxidant properties and the associated health benefits. The growing …