Three decades of ultrasound contrast agents: a review of the past, present and future improvements
P Frinking, T Segers, Y Luan, F Tranquart - Ultrasound in medicine & …, 2020 - Elsevier
Initial reports from the 1960s describing the observations of ultrasound contrast
enhancement by tiny gaseous bubbles during echocardiographic examinations prompted …
enhancement by tiny gaseous bubbles during echocardiographic examinations prompted …
Drug delivery system based on nanobubbles
J Jin, L Yang, F Chen, N Gu - Interdisciplinary Materials, 2022 - Wiley Online Library
Ultrasound (US) medical technology is widely used due to its advantages of safety, speed,
and low cost. With the rapid development of biomedical nanotechnology …
and low cost. With the rapid development of biomedical nanotechnology …
A review of the current therapies, challenges, and future directions of transcranial focused ultrasound technology: advances in diagnosis and treatment
Importance Magnetic resonance imaging–guided focused ultrasound ablation has been
approved for the treatment of refractory essential tremor and is being studied for other …
approved for the treatment of refractory essential tremor and is being studied for other …
Ultrasound-mediated blood–brain barrier disruption for targeted drug delivery in the central nervous system
M Aryal, CD Arvanitis, PM Alexander… - Advanced drug delivery …, 2014 - Elsevier
The physiology of the vasculature in the central nervous system (CNS), which includes the
blood–brain barrier (BBB) and other factors, complicates the delivery of most drugs to the …
blood–brain barrier (BBB) and other factors, complicates the delivery of most drugs to the …
Towards controlled drug delivery in brain tumors with microbubble-enhanced focused ultrasound
Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …
Ultrasound frequency-controlled microbubble dynamics in brain vessels regulate the enrichment of inflammatory pathways in the blood-brain barrier
Microbubble-enhanced ultrasound provides a noninvasive physical method to locally
overcome major obstacles to the accumulation of blood-borne therapeutics in the brain …
overcome major obstacles to the accumulation of blood-borne therapeutics in the brain …
Ultrasound treatment of neurological diseases—current and emerging applications
Like cardiovascular disease and cancer, neurological disorders present an increasing
challenge for an ageing population. Whereas nonpharmacological procedures are routine …
challenge for an ageing population. Whereas nonpharmacological procedures are routine …
Theranostic strategy of focused ultrasound induced blood-brain barrier opening for CNS disease treatment
Focused Ultrasound (FUS) in combination with gaseous microbubbles has emerged as a
potential new means of effective drug delivery to the brain. Recent research has shown that …
potential new means of effective drug delivery to the brain. Recent research has shown that …
Focused ultrasound-mediated drug delivery through the blood–brain barrier
A Burgess, K Shah, O Hough… - Expert review of …, 2015 - Taylor & Francis
Despite recent advances in blood–brain barrier (BBB) research, it remains a significant
hurdle for the pharmaceutical treatment of brain diseases. Focused ultrasound (FUS) is one …
hurdle for the pharmaceutical treatment of brain diseases. Focused ultrasound (FUS) is one …
[HTML][HTML] Combining microbubbles and ultrasound for drug delivery to brain tumors: current progress and overview
Malignant glioma is one of the most challenging central nervous system (CNS) diseases,
which is typically associated with high rates of recurrence and mortality. Current surgical …
which is typically associated with high rates of recurrence and mortality. Current surgical …