A review on lymphocyte radiosensitivity and its impact on radiotherapy
H Paganetti - Frontiers in Oncology, 2023 - frontiersin.org
It is well known that radiation therapy causes lymphopenia in patients and that this is
correlated with a negative outcome. The mechanism is not well understood because …
correlated with a negative outcome. The mechanism is not well understood because …
Toward precision medicine in glioblastoma: the promise and the challenges
Integrated sequencing strategies have provided a broader understanding of the genomic
landscape and molecular classifications of multiple cancer types and have identified various …
landscape and molecular classifications of multiple cancer types and have identified various …
Integrating different data types by regularized unsupervised multiple kernel learning with application to cancer subtype discovery
NK Speicher, N Pfeifer - Bioinformatics, 2015 - academic.oup.com
Motivation: Despite ongoing cancer research, available therapies are still limited in quantity
and effectiveness, and making treatment decisions for individual patients remains a hard …
and effectiveness, and making treatment decisions for individual patients remains a hard …
Nanoparticle designs for delivery of nucleic acid therapeutics as brain cancer therapies
Glioblastoma (GBM) is an aggressive central nervous system cancer with a dismal
prognosis. The standard of care involves surgical resection followed by radiotherapy and …
prognosis. The standard of care involves surgical resection followed by radiotherapy and …
Predicting clinical outcomes in glioblastoma: an application of topological and functional data analysis
Glioblastoma multiforme (GBM) is an aggressive form of human brain cancer that is under
active study in the field of cancer biology. Its rapid progression and the relative time cost of …
active study in the field of cancer biology. Its rapid progression and the relative time cost of …
In vitro and in vivo enhancement of temozolomide effect in human glioblastoma by non-invasive application of cold atmospheric plasma
Simple Summary Glioblastoma (GBM) is an aggressive type of brain cancer, with which only
25% of patients survive for more than one year. Treatment of GBM has remained a …
25% of patients survive for more than one year. Treatment of GBM has remained a …
Breaching barriers in glioblastoma. Part I: Molecular pathways and novel treatment approaches
A Miranda, M Blanco-Prieto, J Sousa, A Pais… - International journal of …, 2017 - Elsevier
Glioblastoma multiforme (GBM) is the most common primary brain tumour, and the most
aggressive in nature. The prognosis for patients with GBM remains poor, with a median …
aggressive in nature. The prognosis for patients with GBM remains poor, with a median …
Dendritic cells and cancer immunotherapy: The adjuvant effect
S Nava, D Lisini, S Frigerio, A Bersano - International Journal of …, 2021 - mdpi.com
Dendritic cells (DCs) are immune specialized cells playing a critical role in promoting
immune response against antigens, and may represent important targets for therapeutic …
immune response against antigens, and may represent important targets for therapeutic …
Sulforaphane enhances temozolomide‐induced apoptosis because of down‐regulation of miR‐21 via Wnt/β‐catenin signaling in glioblastoma
FM Lan, Q Pan, H Yu, X Yue - Journal of neurochemistry, 2015 - Wiley Online Library
Temozolomide (TMZ) has been widely used in the treatment of glioblastoma (GBM),
although inherent or acquired resistance restricts the application. This study was aimed to …
although inherent or acquired resistance restricts the application. This study was aimed to …
Extracellular Matrix Proteins Confer Cell Adhesion-Mediated Drug Resistance Through Integrin αv in Glioblastoma Cells
Chemotherapy resistance to glioblastoma (GBM) remains an obstacle that is difficult to
overcome, leading to poor prognosis of GBM patients. Many previous studies have focused …
overcome, leading to poor prognosis of GBM patients. Many previous studies have focused …