Since the formal characterization of sleep stages, there have been reports that seizures may
preferentially occur in certain phases of sleep. Through ascending cholinergic connections …

Sleepis one of the best-documented factors influencing the expression of seizuresand
interictal discharges. Janz studied the relation between seizures and thesleep/wake cycle …

Epileptic discharges in focal epilepsy are frequently activated during non-rapid eye
movement sleep. Sleep slow waves are present during this stage and have been shown to …

Objective: To evaluate the effects of sleep on partial seizures arising from various brain
regions. Methods: The authors prospectively studied 133 patients with localization-related …

Purpose: Previous studies of patients with epilepsy and animal models of epilepsy suggest
that sleep increases the frequency, duration, and secondary generalization of seizures. This …

Purpose: To test the hypothesis that deepening sleep activates focal interictal epileptiform
discharges (IEDs), we performed EEG‐polysomnography in 21 subjects with medically …

This targeted review addresses the best accepted and most intriguing recent observations
on the complex relationships between sleep and epilepsy. Ten to 15% of all epilepsies are …

Objective Rapid eye movement (REM) sleep has a suppressing effect on epileptic activity.
This effect might be directly related to neuronal desynchronization mediated by cholinergic …

An electroencephalogram (EEG) recorded after sleep deprivation (SDEEG) in epilepsy
patients often discloses epileptiform discharges (ED) when routine EEG (REEG) does not …

In animal studies, both seizures and interictal spikes induce synaptic potentiation. Recent
evidence suggests that electroencephalogram slow wave activity during sleep reflects …