Like all retroviruses, the human immunodeficiency virus selectively packages two copies of
its unspliced RNA genome, both of which are utilized for strand-transfer-mediated …

Publisher Summary This chapter focuses on recent biochemical and biophysical studies that
examine the nucleic acid chaperone function of HIV‐1 nucleocapsid protein (NC) and its …

Retrovirus particles contain a small, basic protein, the nucleocapsid (NC) protein, that
possessesnucleic acid chaperone'activity-that is, the NC protein can catalyze the …

Retroviruses are a family of widespread small animal viruses about 110 nm in diameter,
composed of an inner core surrounded by an outer envelope formed of a lipid bilayer of …

Human immunodeficiency virus type 1 (HIV-1) and other retroviruses replicate through
reverse transcription, a process in which the single stranded RNA of the viral genome is …

The nucleocapsid protein (NC) of human immunodeficiency virus type 1 (HIV-1) has two zinc
fingers, each containing the invariant metal ion binding residues CCHC. Recent reports …

Nucleocapsid protein 7 (NCp7), the human immunodeficiency virus type 1 (HIV-1)
nucleocapsid protein, was shown to strongly potentiate the dimerization of the retroviral …

RNA chaperones are ubiquitous and abundant proteins found in all living organisms and
viruses, where they interact with various classes of RNA. These highly diverse families of …

The nucleocapsid protein NCp7 of HIV-1 Mal contains two successive Zn knuckles of the
CX2CX4HX4C type and plays a major role in virion morphogenesis, genomic RNA …

Two DNA strand transfers are required during reverse transcription of the RNA genome of
retroviruses to complete provirus synthesis. To understand more about the first strand …