Solid-state nanopore sensors

L Xue, H Yamazaki, R Ren, M Wanunu… - Nature Reviews …, 2020 - nature.com
Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

Surface coatings for solid-state nanopores

OM Eggenberger, C Ying, M Mayer - Nanoscale, 2019 - pubs.rsc.org
Since their introduction in 2001, solid-state nanopores have been increasingly exploited for
the detection and characterization of biomolecules ranging from single DNA strands to …

Estimation of shape, volume, and dipole moment of individual proteins freely transiting a synthetic nanopore

J Houghtaling, C Ying, OM Eggenberger, A Fennouri… - ACS …, 2019 - ACS Publications
This paper demonstrates that high-bandwidth current recordings in combination with low-
noise silicon nitride nanopores make it possible to determine the molecular volume …

[HTML][HTML] Noise in nanopore sensors: Sources, models, reduction, and benchmarking

S Liang, F Xiang, Z Tang, R Nouri, X He… - Nanotechnology and …, 2020 - pubs.aip.org
Label-free nanopore sensors have emerged as a new generation technology of DNA
sequencing and have been widely used for single molecule analysis. Since the first α …

From water solutions to ionic liquids with solid state nanopores as a perspective to study transport and translocation phenomena

S Marion, N Vučemilović‐Alagić, M Špadina… - Small, 2021 - Wiley Online Library
Solid state nanopores are single‐molecular devices governed by nanoscale physics with a
broad potential for technological applications. However, the control of translocation speed in …

Devices for Nanoscale Guiding of DNA through a 2D Nanopore

DJ Niedzwiecki, B DiPaolo, CY Lin, A Castan… - ACS …, 2021 - ACS Publications
We fabricate on-chip solid-state nanofluidic-2D nanopore systems that can limit the range of
motion for DNA in the sensing region of a nanopore. We do so by creating devices …

Watching single unmodified enzymes at work

C Ying, E Karakaci, E Bermudez-Urena, A Ianiro… - arXiv preprint arXiv …, 2021 - arxiv.org
Many proteins undergo conformational changes during their activity. A full understanding of
the function of these proteins can only be obtained if different conformations and transitions …

Structure Design of Silicon Based Nanopore Chips for Noise Reduction

W Liu, Y Zhang, Z Gu, F Zheng, J Sha… - IEEE Sensors …, 2023 - ieeexplore.ieee.org
Solid-state nanopores have promising applications in single-molecule detection, including
deoxyribonucleic acid (DNA), ribonucleic acid (RNA), proteins, and so on. However, the …

Localized Nanopore Fabrication via Controlled Breakdown

C Ying, T Ma, L Xu, M Rahmani - Nanomaterials, 2022 - mdpi.com
Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and
other biomolecules without the need for fluorescent labeling or chemical modifications. Solid …

Wafer-scale fabrication of uniform, micrometer-sized, triangular membranes on sapphire for high-speed protein sensing in a nanopore

P Xia, MA Rahman Laskar, C Wang - ACS applied materials & …, 2023 - ACS Publications
Ultra-low-noise solid-state nanopores are attractive for high-accuracy single-molecule
sensing. A conventional silicon platform introduces acute capacitive noise to the system …