Fungal secondary metabolism: regulation, function and drug discovery
NP Keller - Nature Reviews Microbiology, 2019 - nature.com
One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
Growing a circular economy with fungal biotechnology: a white paper
Fungi have the ability to transform organic materials into a rich and diverse set of useful
products and provide distinct opportunities for tackling the urgent challenges before all …
products and provide distinct opportunities for tackling the urgent challenges before all …
Mycotoxins in conversation with bacteria and fungi
N Venkatesh, NP Keller - Frontiers in microbiology, 2019 - frontiersin.org
An important goal of the mycotoxin research community is to develop comprehensive
strategies for mycotoxin control and detoxification. Although significant progress has been …
strategies for mycotoxin control and detoxification. Although significant progress has been …
On top of biosynthetic gene clusters: How epigenetic machinery influences secondary metabolism in fungi
BT Pfannenstiel, NP Keller - Biotechnology advances, 2019 - Elsevier
Fungi produce an abundance of bioactive secondary metabolites which can be utilized as
antibiotics and pharmaceutical drugs. The genes encoding secondary metabolites are …
antibiotics and pharmaceutical drugs. The genes encoding secondary metabolites are …
Biosynthetic gene clusters and the evolution of fungal chemodiversity
Covering: up to 2019 Fungi produce a remarkable diversity of secondary metabolites: small,
bioactive molecules not required for growth but which are essential to their ecological …
bioactive molecules not required for growth but which are essential to their ecological …
[HTML][HTML] Wood decay fungi and their bacterial interaction partners in the built environment–A systematic review on fungal bacteria interactions in dead wood and …
J Embacher, S Zeilinger, M Kirchmair… - Fungal Biology …, 2023 - Elsevier
Microbial biodeterioration of timber and woody material in buildings can cause costly
restoration procedures. Here, we focus on Serpula lacrymans (commonly known as dry-rot) …
restoration procedures. Here, we focus on Serpula lacrymans (commonly known as dry-rot) …
Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability
Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through
its interactions with growing and decaying flora and their constituent microbiomes. The …
its interactions with growing and decaying flora and their constituent microbiomes. The …
Bacterial–fungal interactions revealed by genome-wide analysis of bacterial mutant fitness
Microbial interactions are expected to be major determinants of microbiome structure and
function. Although fungi are found in diverse microbiomes, their interactions with bacteria …
function. Although fungi are found in diverse microbiomes, their interactions with bacteria …
Expanding the chemical diversity through microorganisms co-culture: Current status and outlook
Natural products (NPs) are considered as a cornerstone for the generation of bioactive leads
in drug discovery programs. However, one of the major limitations of NP drug discovery …
in drug discovery programs. However, one of the major limitations of NP drug discovery …
Bacterial hitchhikers derive benefits from fungal housing
Fungi and bacteria are ubiquitous constituents of all microbiomes, yet mechanisms of
microbial persistence in polymicrobial communities remain obscure. Here, we examined the …
microbial persistence in polymicrobial communities remain obscure. Here, we examined the …