[HTML][HTML] Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation

NA Trayanova, A Lyon, J Shade… - Physiological …, 2023 - pmc.ncbi.nlm.nih.gov
The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Whole-heart ventricular arrhythmia modeling moving forward: Mechanistic insights and translational applications

E Sung, S Etoz, Y Zhang, NA Trayanova - Biophysics reviews, 2021 - pubs.aip.org
Ventricular arrhythmias are the primary cause of sudden cardiac death and one of the
leading causes of mortality worldwide. Whole-heart computational modeling offers a unique …

Personalized digital-heart technology for ventricular tachycardia ablation targeting in hearts with infiltrating adiposity

E Sung, A Prakosa, KN Aronis, S Zhou… - Circulation …, 2020 - Am Heart Assoc
Background: Infiltrating adipose tissue (inFAT) is a newly recognized proarrhythmic
substrate for postinfarct ventricular tachycardias (VT) identifiable on contrast-enhanced …

[HTML][HTML] Role of miRNA–mRNA Interactome in Pathophysiology of Arrhythmogenic Cardiomyopathy

F Bonet, O Campuzano, J Córdoba-Caballero… - Biomedicines, 2024 - mdpi.com
Arrhythmogenic cardiomyopathy is an inherited entity characterized by irregular cell–cell
adhesion, cardiomyocyte death and fibro-fatty replacement of ventricular myocytes, leading …

Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation

NA Trayanova, A Lyon, J Shade… - Physiological …, 2024 - journals.physiology.org
The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Relationship between epicardial adipose tissue measured by computed tomography and premature ventricular complexes originating from different sites

J Shen, D Zhu, L Chen, J Cang, Z Zhao, Y Ji, S Liu… - Europace, 2023 - academic.oup.com
Aims This study aims to explore the association between the features of epicardial adipose
tissue (EAT) in different zones and premature ventricular complexes (PVCs) originating from …

Novel algorithm for diagnosis of Arrhythmogenic cardiomyopathy and dilated cardiomyopathy: Key gene expression profiling using machine learning

Y Zhang, J Xie, Y Wu, B Zhang, C Zhou… - The Journal of Gene …, 2023 - Wiley Online Library
Background It is difficult to distinguish between arrhythmogenic cardiomyopathy (ACM) and
dilated cardiomyopathy (DCM) because of their similar clinical manifestations. This study …

Epicardial conduction speed, electrogram abnormality, and computed tomography attenuation associations in arrhythmogenic right ventricular cardiomyopathy

T Ustunkaya, B Desjardins, R Wedan… - JACC: Clinical …, 2019 - jacc.org
Objectives: This study sought to evaluate the association between contrast-enhanced
multidetector computed tomography (CE-MDCT) attenuation and local epicardial conduction …

Cardiac adiposity and arrhythmias: The role of imaging

M Bonou, S Mavrogeni, CJ Kapelios… - Diagnostics, 2021 - mdpi.com
Increased cardiac fat depots are metabolically active tissues that have a pronounced pro-
inflammatory nature. Increasing evidence supports a potential role of cardiac adiposity as a …

心脏CT 平扫与CTA 定量分析心外膜脂肪体积对比研究

程凯, 查云飞, 胡磊, 曾菲菲, 彭宙锋 - CT 理论与应用研究, 2019 - cttacn.org.cn
目的: 对比研究基于心电门控的心脏CT 平扫(NCT) 与冠状动脉CTA 定量评价冠心病患者心外膜
脂肪体积(EFV) 的一致性. 方法: 回顾性分析临床诊断冠心病同期行心脏CT 平扫和冠状动脉CTA …