MicroRNAs and synaptic plasticity—a mutual relationship

A Aksoy-Aksel, F Zampa… - … Transactions of the …, 2014 - royalsocietypublishing.org
MicroRNAs (miRNAs) are rapidly emerging as central regulators of gene expression in the
postnatal mammalian brain. Initial studies mostly focused on the function of specific miRNAs …

MicroRNA and epilepsy: profiling, functions and potential clinical applications

DC Henshall - Current opinion in neurology, 2014 - journals.lww.com
MicroRNA and epilepsy: profiling, functions and potential cl... : Current Opinion in Neurology
MicroRNA and epilepsy: profiling, functions and potential clinical applications : Current …

A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar …

SS Hébert, WX Wang, Q Zhu… - Journal of Alzheimer's …, 2013 - content.iospress.com
MicroRNAs (miRNAs) are small (20-22 nucleotides) regulatory non-coding RNAs that
strongly influence gene expression. Most prior studies addressing the role of miRNAs in …

Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures

M van Spronsen, EY van Battum, M Kuijpers… - PLoS …, 2013 - journals.plos.org
MicroRNAs (miRNAs) are evolutionarily conserved non-coding RNAs of∼ 22 nucleotides
that regulate gene expression at the level of translation and play vital roles in hippocampal …

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

MT Venø, CR Reschke, G Morris… - Proceedings of the …, 2020 - National Acad Sciences
Temporal lobe epilepsy is the most common drug-resistant form of epilepsy in adults. The
reorganization of neural networks and the gene expression landscape underlying …

miRNAs: biological and clinical determinants in epilepsy

WA Alsharafi, B Xiao, MM Abuhamed… - Frontiers in molecular …, 2015 - frontiersin.org
Recently, microRNAs (miRNAs) are reported to be crucial modulators in the pathogenesis
and potential treatment of epilepsies. To date, several miRNAs have been demonstrated to …

Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression

YB Wei, JJ Liu, JC Villaescusa, E Åberg… - Translational …, 2016 - nature.com
Elevation of the proinflammatory cytokine IL-6 has been implicated in depression; however,
the mechanisms remain elusive. MicroRNAs (miRNAs) are small non-coding RNAs that …

Glial responses during epileptogenesis in Mus musculus point to potential therapeutic targets

G Kalozoumi, O Kel-Margoulis, E Vafiadaki… - PLoS …, 2018 - journals.plos.org
The Mesio-Temporal Lobe Epilepsy syndrome is the most common form of intractable
epilepsy. It is characterized by recurrence of focal seizures and is often associated with …

miRNA changes in retinal ganglion cells after optic nerve crush and glaucomatous damage

B Mead, A Kerr, N Nakaya, SI Tomarev - Cells, 2021 - mdpi.com
The purpose of this study was to characterize the miRNA profile of purified retinal ganglion
cells (RGC) from healthy and diseased rat retina. Diseased retina includes those after a …

Transcript specificity in BDNF-regulated protein synthesis

CR Ruiz, J Shi, MK Meffert - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor (BDNF) is a critical activity-dependent modulator of gene
expression, which can regulate both transcription and translation. Several functions of …