Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Transient receptor potential (TRP) channels are a group of membrane proteins involved in
the transduction of a plethora of chemical and physical stimuli. These channels modulate ion …

The endocannabinoid signalling system was discovered because receptors in this system
are the targets of compounds present in psychotropic preparations of Cannabis sativa. The …

The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient
China and Egypt. While marijuana has recently shown promise in managing chronic pain …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

The endocannabinoid system is currently defined as the ensemble of the two 7-
transmembrane-domain and G protein-coupled receptors for Δ 9-tetrahydrocannabinol (but …

The endocannabinoid system consists of G protein-coupled cannabinoid CB 1 and CB 2
receptors, of endogenous compounds known as endocannabinoids that can target these …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

There are at least two types of cannabinoid receptors (CB1 and CB2). Ligands activating
these G protein-coupled receptors (GPCRs) include the phytocannabinoid Δ9 …

BACKGROUND AND PURPOSE Cannabidiol (CBD) and Δ9‐tetrahydrocannabinol (THC)
interact with transient receptor potential (TRP) channels and enzymes of the …