Motor behavioral deficits in the cuprizone model: Validity of the rotarod test paradigm

C Lubrich, P Giesler, M Kipp - International journal of molecular sciences, 2022 - mdpi.com
Multiple Sclerosis (MS) is a neuroinflammatory disorder, which is histopathologically
characterized by multifocal inflammatory demyelinating lesions affecting both the central …

Antiinflammatory activity of natural triterpenes—An overview from 2006 to 2021

RS Miranda, BSM de Jesus… - Phytotherapy …, 2022 - Wiley Online Library
Terpenes are one of the most abundant classes of secondary metabolites produced by
plants and can be divided based on the number of isoprene units (C5) in monoterpenes (2 …

Neuroprotective properties of Betulin, Betulinic acid, and Ursolic acid as triterpenoids derivatives: A comprehensive review of mechanistic studies

M Farzan, M Farzan, M Shahrani, SP Navabi… - Nutritional …, 2024 - Taylor & Francis
Cognitive deficits are the main outcome of neurological disorders whose occurrence has
risen over the past three decades. Although there are some pharmacologic approaches …

Impact of calcitriol and PGD2-G-loaded lipid nanocapsules on oligodendrocyte progenitor cell differentiation and remyelination

A Mwema, V Gratpain, B Ucakar… - Drug Delivery and …, 2024 - Springer
Multiple sclerosis (MS) is a demyelinating and inflammatory disease of the central nervous
system (CNS) in need of a curative treatment. MS research has recently focused on the …

Natural products targeting cellular processes common in Parkinson's disease and multiple sclerosis

X Xu, C Han, P Wang, F Zhou - Frontiers in Neurology, 2023 - frontiersin.org
The hallmarks of Parkinson's disease (PD) include the loss of dopaminergic neurons and
formation of Lewy bodies, whereas multiple sclerosis (MS) is an autoimmune disorder with …

[HTML][HTML] Promoting remyelination in central nervous system diseases: potentials and prospects of natural products and herbal medicine

H Zhu, E Hu, X Guo, Z Yuan, H Jiang, W Zhang… - Pharmacological …, 2024 - Elsevier
Myelin damage is frequently associated with central nervous system (CNS) diseases and is
a critical factor influencing neurological function and disease prognosis. Nevertheless, the …

Suppressive effect of fruiting bodies of medicinal mushrooms on demyelination and motor dysfunction in a Cuprizone-induced multiple sclerosis mouse model

K Yamashina, S Yamamoto… - … Journal of Medicinal …, 2022 - dl.begellhouse.com
Epidemiologic studies have shown a high prevalence of multiple sclerosis (MS) in Europe
and North America, and a low prevalence in East Asia. Mushrooms contain various …

[HTML][HTML] Antioxidant Therapies in the Treatment of Multiple Sclerosis

FJ Jiménez-Jiménez, H Alonso-Navarro… - Biomolecules, 2024 - mdpi.com
Several studies have proposed a potential role for oxidative stress in the development of
multiple sclerosis (MS). For this reason, it seems tentative to think that treatment with …

Efforts Towards Repurposing of Antioxidant Drugs and Active Compounds for Multiple Sclerosis Control

P Theodosis-Nobelos, EA Rekka - Neurochemical Research, 2023 - Springer
Multiple Sclerosis (MS) is a degenerative disorder of the central nervous system (CNS) with
complicated etiology that has not been clearly analyzed until nowadays. Apart from anti …

Ursolic acid derivative UAOS-Na treats experimental autoimmune encephalomyelitis by immunoregulation and protecting myelin

M Wang, C Gu, Y Yang, L Chen, K Chen, J Du… - Frontiers in …, 2023 - frontiersin.org
Introduction Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central
nervous system (CNS). Ursolic acid (UA) can be used in the MS treatment with anti …