The application of virus-like particles as vaccines and biological vehicles

D Yan, YQ Wei, HC Guo, SQ Sun - Applied microbiology and …, 2015 - Springer
Virus-like particles (VLPs) can be spontaneously self-assembled by viral structural proteins
under appropriate conditions in vitro while excluding the genetic material and potential …

Current status and perspective on the use of viral-based vectors in eukaryotic microalgae

OC Bolaños-Martínez, G Mahendran… - Marine Drugs, 2022 - mdpi.com
During the last two decades, microalgae have attracted increasing interest, both
commercially and scientifically. Commercial potential involves utilizing valuable natural …

Expression of Chimeric HPV-HIV Protein L1P18 in Pichia pastoris; Purification and Characterization of the Virus-like Particles

Y Eto, N Saubi, P Ferrer, J Joseph-Munné - Pharmaceutics, 2021 - mdpi.com
Currently, three human papillomavirus (HPV) vaccines are already licensed and all of them
are based on virus-like particles (VLPs) of HPV L1 capsid protein but not worldwide …

Anti-human CD138 monoclonal antibodies and their bispecific formats: generation and characterization

D Chen, J Zou, Y Zong, H Meng, G An… - Immunopharmacology …, 2016 - Taylor & Francis
Abstract Syndecan-1 (CD138), a heparan sulfate proteoglycan, acts as a co-receptor for
growth factors and chemokines and is a molecular marker associated with the epithelial …

Quantitation and biospecific identification of virus-like particles of human papillomavirus by capillary electrophoresis

V Bettonville, JTJ Nicol, T Furst, N Thelen, G Piel… - Talanta, 2017 - Elsevier
Capillary electrophoresis (CE) for HPV-VLP quantitation is a very interesting alternative
technique compared to those currently used in viral analysis, such as SDS-PAGE, Western …

Quantitative and epitope-specific antigenicity analysis of the human papillomavirus 6 capsid protein in aqueous solution or when adsorbed on particulate adjuvants

M Li, X Wang, L Cao, Z Lin, M Wei, M Fang, S Li… - Vaccine, 2016 - Elsevier
Human papillomavirus (HPV) 6 is a human pathogen which causes genital warts.
Recombinant virus-like particle (VLP) based antigens are the active components in …

Immunotherapeutic strategies for sexually transmitted viral infections: HIV, HSV and HPV

B Wahid, A Ali, M Idrees, S Rafique - Cellular Immunology, 2016 - Elsevier
More than 1 million sexually transmitted infections (STIs) are acquired each day globally.
Etiotropic drugs cannot effectively control infectious diseases therefore, there is a dire need …

Evaluación de ensayos serológicos para la identificación de anticuerpos neutralizantes contra HPV-16 en mujeres vacunadas contra HPV

KLS FLORES - 2023 - riaa.uaem.mx
Introducción: El cáncer de cuello uterino (CC) representa un problema de salud pública al
estar entre los primeros lugares de incidencia y mortalidad a nivel mundial. En México, el …

[PDF][PDF] 抗HPV11 病毒样颗粒单克隆抗体的性质鉴定及初步应用

李敏, 林知捷, 魏旻希, 李少伟, 夏宁邵, 赵勤俭 - 中国生化药物杂志, 2016 - core.ac.uk
目的分析和鉴定抗HPV11 病毒样颗粒(virus-like particle, VLP) 鼠源单克隆抗体的性质,
筛选性质和生物学活性较优的抗体, 并初步应用于抗原或疫苗的质量分析. 方法分别利用间接 …

[HTML][HTML] An innovative method of nonclinical efficacy and toxicological evaluation of recombinant Salmonella typhi Ty21a expressing HPV16 and 18 L1 proteins

YS Reddy, KN Babu, S Qadri, MV Surekha, BD Kumar - MethodsX, 2021 - Elsevier
Advancement in technology led to development of live attenuated Salmonella typhi Ty21a
as enteric vector for expression of foreign proteins. Such vector platform is inevitable for …