Hemostatic biomaterials to halt non-compressible hemorrhage

S Jiang, S Liu, S Lau, J Li - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Non-compressible hemorrhage is an unmet clinical challenge, which occurs in inaccessible
sites in the body where compression cannot be applied to stop bleeding. Current treatments …

Viscoelastic biomaterials for tissue regeneration

DT Wu, N Jeffreys, M Diba… - Tissue Engineering Part C …, 2022 - liebertpub.com
The extracellular matrix (ECM) mechanical properties regulate key cellular processes in
tissue development and regeneration. The majority of scientific investigation has focused on …

Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage

G Bao, Q Gao, M Cau, N Ali-Mohamad… - Nature …, 2022 - nature.com
Non-compressible hemorrhage is an unmet clinical challenge that accounts for high
mortality in trauma. Rapid pressurized blood flows under hemorrhage impair the function …

[HTML][HTML] Fracture toughness of fibrin gels as a function of protein volume fraction: Mechanical origins

K Garyfallogiannis, RK Ramanujam, RI Litvinov, T Yu… - Acta Biomaterialia, 2023 - Elsevier
The mechanical stability of blood clots necessary for their functions is provided by fibrin, a
fibrous gel. Rupture of clots leads to life-threatening thrombotic embolization, which is little …

Hydrophilic chitosan/graphene oxide composite sponge for rapid hemostasis and non-rebleeding removal

F Du, A Wenjing, F Liu, B Wu, Y Liu, W Zheng… - Carbohydrate …, 2023 - Elsevier
Hydrophilic hemostatic sponge plays an important role in trauma bleeding control because
of its robust coagulant functions. However, its strong tissue adhesion can easily result in …

A review on the association of thrombus composition with mechanical and radiological imaging characteristics in acute ischemic stroke

R Cahalane, N Boodt, AC Akyildiz, J Giezen… - Journal of …, 2021 - Elsevier
Thrombus composition and mechanical properties significantly impact the ease and
outcomes of thrombectomy procedures in patients with acute ischemic stroke. A wide …

Blood clot behaves as a poro-visco-elastic material

F Ghezelbash, S Liu, A Shirazi-Adl, J Li - Journal of the Mechanical …, 2022 - Elsevier
Mechanical properties of blood clots play a crucial role in hemostasis and embolization.
They are time-dependent and often described with viscoelastic models. But blood clots also …

A speckling technique for DIC on ultra-soft, highly hydrated materials

GP Sugerman, J Yang, MK Rausch - Experimental Mechanics, 2023 - Springer
Background Digital image correlation is a useful tool in many engineering disciplines to
measure and visualize deformation fields. Noteworthily, its successful application is critically …

Advances in 3D bioprinting of biomimetic and engineered meniscal grafts

H Lv, G Deng, J Lai, Y Yu, F Chen… - Macromolecular …, 2023 - Wiley Online Library
The meniscus plays a crucial role in loads distribution and protection of articular cartilage.
Meniscal injury can result in cartilage degeneration, loss of mechanical stability in the knee …

Elasticity of whole blood clots measured via Volume Controlled Cavity Expansion

H Varner, GP Sugerman, MK Rausch… - Journal of the Mechanical …, 2023 - Elsevier
Measuring and understanding the mechanical properties of blood clots can provide insights
into disease progression and the effectiveness of potential treatments. However, several …