Background Sleep and circadian rhythm disturbances in schizophrenia are common, but
incompletely characterized. We aimed to describe and compare the magnitude and …

Psychotic symptoms, that we defined as delusions or hallucinations, are common in bipolar
disorders (BD). This systematic review and meta-analysis aims to synthesise the literature …

The Akt family of kinases exerts many of its cellular effects via the activation of the
mammalian target of rapamycin (mTOR) kinase through a series of intermediary proteins …

Background There are limited studies on the prevalence of misdiagnosis as well as
detection rates of severe psychiatric disorders in specialized and non-specialized …

Many published books that comment on the medical model have been written by doctors,
who assume that readers have the same knowledge of medicine, or by those who have …

BACKGROUND Lifetime psychotic symptoms are present in over half of the patients with
bipolar disorder (BD) and can have an adverse effect on its course, outcome, and treatment …

Background Low-grade inflammation has been implicated in the pathophysiology of severe
mental disorders (SMDs) and a link between immune activation and clinical characteristics …

BackgroundThe course of Bipolar Disorder (BD) is highly variable, with marked inter and
intra-individual differences in symptoms and functioning. In this study, we identified illness …

The ability to classify patients with bipolar disorder (BD) is restricted by their heterogeneity,
which limits the understanding of their neuropathology. Therefore, we aimed to investigate …

(1) Background: bipolar disorder (BD) is a chronic disease that often leads to functional
impairment. The objective of this study is to elucidate which variables are associated with …