Intracellular signalling pathways activated by leptin
G Frühbeck - Biochemical Journal, 2006 - portlandpress.com
Leptin is a versatile 16 kDa peptide hormone, with a tertiary structure resembling that of
members of the long-chain helical cytokine family. It is mainly produced by adipocytes in …
members of the long-chain helical cytokine family. It is mainly produced by adipocytes in …
Resident vascular endothelial progenitor definition and function: the age of reckoning
J Dight, J Zhao, C Styke, K Khosrotehrani, J Patel - Angiogenesis, 2022 - Springer
The cardiovascular system is composed around the central function of the endothelium that
lines the inner surfaces of its vessels. In recent years, the existence of a progenitor …
lines the inner surfaces of its vessels. In recent years, the existence of a progenitor …
Heteroaryl substituted pyrrolo [2, 3-b] pyridines and pyrrolo [2, 3-b] pyrimidines as janus kinase inhibitors
JD Rodgers, S Shepard - US Patent 7,598,257, 2009 - Google Patents
2007-02-06 Assigned to INCYTE CORPORATION reassignment INCYTE CORPORATION
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
[HTML][HTML] Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer
A Li, J King, A Moro, MD Sugi, DW Dawson… - The American journal of …, 2011 - Elsevier
Epithelial neutrophil-activating peptide-78 (CXCL5), a member of the CXC chemokine
family, has been shown to be involved in angiogenesis, tumor growth, and metastasis. The …
family, has been shown to be involved in angiogenesis, tumor growth, and metastasis. The …
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors
JD Rodgers, S Shepard, W Zhu, L Shao… - US Patent …, 2015 - Google Patents
2012-03-14 Assigned to INCYTE CORPORATION reassignment INCYTE CORPORATION
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Piperidin-4-yl azetidine derivatives as JAK1 inhibitors
T Huang, CB Xue, HY Li, Q Li - US Patent 8,765,734, 2014 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
44065466&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
44065466&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
T Cao, W Zhang, Q Wang, C Wang, W Ma, C Zhang… - Cell, 2024 - cell.com
Taurine is used to bolster immunity, but its effects on antitumor immunity are unclear. Here,
we report that cancer-related taurine consumption causes T cell exhaustion and tumor …
we report that cancer-related taurine consumption causes T cell exhaustion and tumor …
Cyclohexyl azetidine derivatives as jak inhibitors
JD Rodgers, AG Arvanitis - US Patent 9,359,358, 2016 - Google Patents
US9359358B2 - Cyclohexyl azetidine derivatives as JAK inhibitors - Google Patents
US9359358B2 - Cyclohexyl azetidine derivatives as JAK inhibitors - Google Patents Cyclohexyl …
US9359358B2 - Cyclohexyl azetidine derivatives as JAK inhibitors - Google Patents Cyclohexyl …
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors
JD Rodgers, W Zhu, J Glenn - US Patent 9,034,884, 2015 - Google Patents
A61P 9/04(2006.01) A61P 9/08(2006.01) I A61P 9/10(2006.01) A61 P21/04(2006.01) A61 P
25/OO(2006.01) A61P 29/00(2006.01) A6IP3/IO(2006.01) A6IP35/OO(2006.01) …
25/OO(2006.01) A61P 29/00(2006.01) A6IP3/IO(2006.01) A6IP35/OO(2006.01) …
Heterocyclic derivatives of pyrazol-4-yl-pyrrolo [2, 3-d] pyrimidines as janus kinase inhibitors
JD Rodgers, YL Li, S Shepard, H Wang - US Patent 9,249,145, 2016 - Google Patents
2015-07-02 Assigned to INCYTE HOLDINGS CORPORATION, INCYTE CORPORATION
reassignment INCYTE HOLDINGS CORPORATION CORRECTIVE ASSIGNMENT TO …
reassignment INCYTE HOLDINGS CORPORATION CORRECTIVE ASSIGNMENT TO …