Use of brain biomechanical models for monitoring impact exposure in contact sports

S Ji, M Ghajari, H Mao, RH Kraft… - Annals of Biomedical …, 2022 - Springer
Head acceleration measurement sensors are now widely deployed in the field to monitor
head kinematic exposure in contact sports. The wealth of impact kinematics data provides …

[HTML][HTML] Mechanosensation in traumatic brain injury

CE Keating, DK Cullen - Neurobiology of disease, 2021 - Elsevier
Traumatic brain injury (TBI) is distinct from other neurological disorders because it is
induced by a discrete event that applies extreme mechanical forces to the brain. This review …

Instantaneous whole-brain strain estimation in dynamic head impact

K Ghazi, S Wu, W Zhao, S Ji - Journal of Neurotrauma, 2021 - liebertpub.com
Head injury models are notoriously time consuming and resource demanding in simulations,
which prevents routine application. Here, we extend a convolutional neural network (CNN) …

An analytical review of the numerical methods used for finite element modeling of traumatic brain injury

JS Giudice, W Zeng, T Wu, A Alshareef… - Annals of biomedical …, 2019 - Springer
Dozens of finite element models of the human brain have been developed for providing
insight into the mechanical response of the brain during impact. Many models used in …

Evaluation of tissue-level brain injury metrics using species-specific simulations

T Wu, M Hajiaghamemar, JS Giudice… - Journal of …, 2021 - liebertpub.com
Traumatic brain injury (TBI) is a significant public health burden, and the development of
advanced countermeasures to mitigate and prevent these injuries during automotive, sports …

In vivo estimates of axonal stretch and 3D brain deformation during mild head impact

AK Knutsen, AD Gomez, M Gangolli, WT Wang… - Brain multiphysics, 2020 - Elsevier
The rapid deformation of brain tissue in response to head impact can lead to traumatic brain
injury. In vivo measurements of brain deformation during non-injurious head impacts are …

MR Imaging of Human Brain Mechanics In Vivo: New Measurements to Facilitate the Development of Computational Models of Brain Injury

PV Bayly, A Alshareef, AK Knutsen, K Upadhyay… - Annals of biomedical …, 2021 - Springer
Computational models of the brain and its biomechanical response to skull accelerations
are important tools for understanding and predicting traumatic brain injuries (TBIs) …

Displacement-and strain-based discrimination of head injury models across a wide range of blunt conditions

W Zhao, S Ji - Annals of biomedical engineering, 2020 - Springer
Successful validation of a head injury model is critical to ensure its biofidelity. However,
there is an ongoing debate on what experimental data are suitable for model validation …

Integrating human and nonhuman primate data to estimate human tolerances for traumatic brain injury

T Wu, F Sato, J Antona-Makoshi… - Journal of …, 2022 - asmedigitalcollection.asme.org
Traumatic brain injury (TBI) contributes to a significant portion of the injuries resulting from
motor vehicle crashes, falls, and sports collisions. The development of advanced …

The White Matter Fiber Tract Deforms Most in the Perpendicular Direction During In Vivo Volunteer Impacts

Z Zhou, C Olsson, TC Gasser, X Li… - Journal of …, 2024 - liebertpub.com
White matter (WM) tract-related strains are increasingly used to quantify brain mechanical
responses, but their dynamics in live human brains during in vivo impact conditions remain …